Smith TK - Search Results

1

Smith TK, Bütikofer P. Smith TK, et al. Mol Biochem Parasitol. 2010 Aug;172(2):66-79. doi: 10.1016/j.molbiopara.2010.04.001. Epub 2010 Apr 9. Mol Biochem Parasitol. 2010. PMID: 20382188 Free PMC article. Review.

2

A synthetic acceptor substrate for Trypanosoma brucei UDP-Gal: GPI anchor side-chain alpha-galactosyltransferases.

Brown JR, Smith TK, Ferguson MA, Field RA. Brown JR, et al. Among authors: smith tk. Bioorg Med Chem Lett. 1998 Aug 4;8(15):2051-4. doi: 10.1016/s0960-894x(98)00359-x. Bioorg Med Chem Lett. 1998. PMID: 9873484

3

The myo-inositol-1-phosphate synthase gene is essential in Trypanosoma brucei.

Martin KL, Smith TK. Martin KL, et al. Among authors: smith tk. Biochem Soc Trans. 2005 Nov;33(Pt 5):983-5. doi: 10.1042/BST0330983. Biochem Soc Trans. 2005. PMID: 16246027

4

Phosphatidylinositol synthesis is essential in bloodstream form Trypanosoma brucei.

Martin KL, Smith TK. Martin KL, et al. Among authors: smith tk. Biochem J. 2006 Jun 1;396(2):287-95. doi: 10.1042/BJ20051825. Biochem J. 2006. PMID: 16475982 Free PMC article.

5

The glycosylphosphatidylinositol (GPI) biosynthetic pathway of bloodstream-form Trypanosoma brucei is dependent on the de novo synthesis of inositol.

Martin KL, Smith TK. Martin KL, et al. Among authors: smith tk. Mol Microbiol. 2006 Jul;61(1):89-105. doi: 10.1111/j.1365-2958.2006.05216.x. Mol Microbiol. 2006. PMID: 16824097 Free PMC article.

6

A novel phospholipase from Trypanosoma brucei.

Richmond GS, Smith TK. Richmond GS, et al. Among authors: smith tk. Mol Microbiol. 2007 Feb;63(4):1078-95. doi: 10.1111/j.1365-2958.2006.05582.x. Mol Microbiol. 2007. PMID: 17238918 Free PMC article.

7

The role and characterization of phospholipase A1 in mediating lysophosphatidylcholine synthesis in Trypanosoma brucei.

Richmond GS, Smith TK. Richmond GS, et al. Among authors: smith tk. Biochem J. 2007 Jul 15;405(2):319-29. doi: 10.1042/BJ20070193. Biochem J. 2007. PMID: 17402937 Free PMC article.

8

Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinases.

Gibellini F, Hunter WN, Smith TK. Gibellini F, et al. Among authors: smith tk. Biochem J. 2008 Oct 1;415(1):135-44. doi: 10.1042/BJ20080435. Biochem J. 2008. PMID: 18489261 Free PMC article.

9

First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness.

Smith TK, Young BL, Denton H, Hughes DL, Wagner GK. Smith TK, et al. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1749-52. doi: 10.1016/j.bmcl.2009.01.083. Epub 2009 Jan 30. Bioorg Med Chem Lett. 2009. PMID: 19217283 Free PMC article.

10

The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei.

Gibellini F, Hunter WN, Smith TK. Gibellini F, et al. Among authors: smith tk. Mol Microbiol. 2009 Sep;73(5):826-43. doi: 10.1111/j.1365-2958.2009.06764.x. Epub 2009 Jun 23. Mol Microbiol. 2009. PMID: 19555461 Free PMC article.

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