Froelich CJ - Search Results

1

Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.

Han J, Goldstein LA, Hou W, Froelich CJ, Watkins SC, Rabinowich H. Han J, et al. Among authors: froelich cj. J Biol Chem. 2010 Jul 16;285(29):22461-72. doi: 10.1074/jbc.M109.086587. Epub 2010 Apr 13. J Biol Chem. 2010. PMID: 20388708 Free PMC article.

2

Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.

Han J, Goldstein LA, Gastman BR, Froelich CJ, Yin XM, Rabinowich H. Han J, et al. Among authors: froelich cj. J Biol Chem. 2004 May 21;279(21):22020-9. doi: 10.1074/jbc.M313234200. Epub 2004 Mar 10. J Biol Chem. 2004. PMID: 15014070 Free article.

3

Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

Buzza MS, Zamurs L, Sun J, Bird CH, Smith AI, Trapani JA, Froelich CJ, Nice EC, Bird PI. Buzza MS, et al. Among authors: froelich cj. J Biol Chem. 2005 Jun 24;280(25):23549-58. doi: 10.1074/jbc.M412001200. Epub 2005 Apr 19. J Biol Chem. 2005. PMID: 15843372 Free article.

4

ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.

Duan H, Orth K, Chinnaiyan AM, Poirier GG, Froelich CJ, He WW, Dixit VM. Duan H, et al. Among authors: froelich cj. J Biol Chem. 1996 Jul 12;271(28):16720-4. doi: 10.1074/jbc.271.28.16720. J Biol Chem. 1996. PMID: 8663294 Free article.

5

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.

Catalán E, Jaime-Sánchez P, Aguiló N, Simon MM, Froelich CJ, Pardo J. Catalán E, et al. Among authors: froelich cj. J Biol Chem. 2015 Mar 13;290(11):6868-77. doi: 10.1074/jbc.M114.631564. Epub 2015 Jan 20. J Biol Chem. 2015. PMID: 25605735 Free PMC article.

6

Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.

Martin P, Pardo J, Schill N, Jöckel L, Berg M, Froelich CJ, Wallich R, Simon MM. Martin P, et al. Among authors: froelich cj. J Biol Chem. 2010 Jun 11;285(24):18918-27. doi: 10.1074/jbc.M109.056028. Epub 2010 Apr 15. J Biol Chem. 2010. PMID: 20395300 Free PMC article.

7

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.

Orth K, Chinnaiyan AM, Garg M, Froelich CJ, Dixit VM. Orth K, et al. Among authors: froelich cj. J Biol Chem. 1996 Jul 12;271(28):16443-6. J Biol Chem. 1996. PMID: 8663580 Free article.

8

Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells.

Dressel R, Raja SM, Höning S, Seidler T, Froelich CJ, von Figura K, Günther E. Dressel R, et al. Among authors: froelich cj. J Biol Chem. 2004 May 7;279(19):20200-10. doi: 10.1074/jbc.M313108200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985351 Free article.

9

A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.

Raja SM, Metkar SS, Höning S, Wang B, Russin WA, Pipalia NH, Menaa C, Belting M, Cao X, Dressel R, Froelich CJ. Raja SM, et al. Among authors: froelich cj. J Biol Chem. 2005 May 27;280(21):20752-61. doi: 10.1074/jbc.M501181200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788411 Free article.

10

BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis.

Jans DA, Sutton VR, Jans P, Froelich CJ, Trapani JA. Jans DA, et al. Among authors: froelich cj. J Biol Chem. 1999 Feb 12;274(7):3953-61. doi: 10.1074/jbc.274.7.3953. J Biol Chem. 1999. PMID: 9933585 Free article.

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