Mc Donald JM - Search Results

1

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM, Selkoe DJ, Ince PG, Walsh DM; Medical Research Council Cognitive Function and Ageing Study. Mc Donald JM, et al. Brain. 2010 May;133(Pt 5):1328-41. doi: 10.1093/brain/awq065. Epub 2010 Apr 19. Brain. 2010. PMID: 20403962 Free PMC article.

2

The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain.

McDonald JM, Cairns NJ, Taylor-Reinwald L, Holtzman D, Walsh DM. McDonald JM, et al. Brain Res. 2012 Apr 23;1450:138-47. doi: 10.1016/j.brainres.2012.02.041. Epub 2012 Feb 24. Brain Res. 2012. PMID: 22440675 Free PMC article.

3

Isolation of low-n amyloid β-protein oligomers from cultured cells, CSF, and brain.

Shankar GM, Welzel AT, McDonald JM, Selkoe DJ, Walsh DM. Shankar GM, et al. Methods Mol Biol. 2011;670:33-44. doi: 10.1007/978-1-60761-744-0_3. Methods Mol Biol. 2011. PMID: 20967581

4

A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ.

O'Nuallain B, Klyubin I, Mc Donald JM, Foster JS, Welzel A, Barry A, Dykoski RK, Cleary JP, Gebbink MF, Rowan MJ, Walsh DM. O'Nuallain B, et al. Among authors: mc donald jm. J Neurochem. 2011 Oct;119(1):189-201. doi: 10.1111/j.1471-4159.2011.07389.x. Epub 2011 Aug 22. J Neurochem. 2011. PMID: 21781116 Free PMC article.

5

Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.

Borlikova GG, Trejo M, Mably AJ, Mc Donald JM, Sala Frigerio C, Regan CM, Murphy KJ, Masliah E, Walsh DM. Borlikova GG, et al. Among authors: mc donald jm. Neurobiol Aging. 2013 May;34(5):1315-27. doi: 10.1016/j.neurobiolaging.2012.10.028. Epub 2012 Nov 22. Neurobiol Aging. 2013. PMID: 23182244 Free PMC article.

6

The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species.

Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM 3rd, Frosch MP, Walsh DM. Mc Donald JM, et al. Alzheimers Dement. 2015 Nov;11(11):1286-305. doi: 10.1016/j.jalz.2015.01.005. Epub 2015 Apr 4. Alzheimers Dement. 2015. PMID: 25846299 Free PMC article.

7

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.

Barry AE, Klyubin I, Mc Donald JM, Mably AJ, Farrell MA, Scott M, Walsh DM, Rowan MJ. Barry AE, et al. Among authors: mc donald jm. J Neurosci. 2011 May 18;31(20):7259-63. doi: 10.1523/JNEUROSCI.6500-10.2011. J Neurosci. 2011. PMID: 21593310 Free PMC article.

8

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites.

Freir DB, Nicoll AJ, Klyubin I, Panico S, Mc Donald JM, Risse E, Asante EA, Farrow MA, Sessions RB, Saibil HR, Clarke AR, Rowan MJ, Walsh DM, Collinge J. Freir DB, et al. Among authors: mc donald jm. Nat Commun. 2011 Jun 7;2:336. doi: 10.1038/ncomms1341. Nat Commun. 2011. PMID: 21654636 Free PMC article.

9

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.

Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, Wüllner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Kumar S, et al. Among authors: mc donald jm. EMBO J. 2011 Jun 1;30(11):2255-65. doi: 10.1038/emboj.2011.138. Epub 2011 Apr 28. EMBO J. 2011. PMID: 21527912 Free PMC article.

10

Tau immunization: a cautionary tale?

Mably AJ, Kanmert D, Mc Donald JM, Liu W, Caldarone BJ, Lemere CA, O'Nuallain B, Kosik KS, Walsh DM. Mably AJ, et al. Among authors: mc donald jm. Neurobiol Aging. 2015 Mar;36(3):1316-32. doi: 10.1016/j.neurobiolaging.2014.11.022. Epub 2014 Dec 30. Neurobiol Aging. 2015. PMID: 25619661

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