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Induction of programmed cell death by inhibition of AKT with the alkylphosphocholine perifosine in in vitro models of platinum sensitive and resistant ovarian cancers.
Engel JB, Schönhals T, Häusler S, Krockenberger M, Schmidt M, Horn E, Köster F, Dietl J, Wischhusen J, Honig A. Engel JB, et al. Among authors: horn e. Arch Gynecol Obstet. 2011 Mar;283(3):603-10. doi: 10.1007/s00404-010-1457-6. Epub 2010 Apr 20. Arch Gynecol Obstet. 2011. PMID: 20405296
Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.
Häusler SF, Montalbán del Barrio I, Strohschein J, Chandran PA, Engel JB, Hönig A, Ossadnik M, Horn E, Fischer B, Krockenberger M, Heuer S, Seida AA, Junker M, Kneitz H, Kloor D, Klotz KN, Dietl J, Wischhusen J. Häusler SF, et al. Among authors: horn e. Cancer Immunol Immunother. 2011 Oct;60(10):1405-18. doi: 10.1007/s00262-011-1040-4. Epub 2011 Jun 3. Cancer Immunol Immunother. 2011. PMID: 21638125 Free PMC article.
The TGF-β-inducible miR-23a cluster attenuates IFN-γ levels and antigen-specific cytotoxicity in human CD8⁺ T cells.
Chandran PA, Keller A, Weinmann L, Seida AA, Braun M, Andreev K, Fischer B, Horn E, Schwinn S, Junker M, Houben R, Dombrowski Y, Dietl J, Finotto S, Wölfl M, Meister G, Wischhusen J. Chandran PA, et al. Among authors: horn e. J Leukoc Biol. 2014 Oct;96(4):633-45. doi: 10.1189/jlb.3A0114-025R. Epub 2014 Jul 16. J Leukoc Biol. 2014. PMID: 25030422
Cognate Nonlytic Interactions between CD8+ T Cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties.
Stein RG, Ebert S, Schlahsa L, Scholz CJ, Braun M, Hauck P, Horn E, Monoranu CM, Thiemann VJ, Wustrow MP, Häusler SF, Montalbán Del Barrio I, Stüber TN, Wölfl M, Dietl J, Rosenwald A, Diessner JE, Wöckel A, Wischhusen J. Stein RG, et al. Among authors: horn e. Cancer Res. 2019 Apr 1;79(7):1507-1519. doi: 10.1158/0008-5472.CAN-18-0387. Epub 2019 Jan 28. Cancer Res. 2019. PMID: 30692216
Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene.
Gupta R, Dittmeier M, Wohlleben G, Nickl V, Bischler T, Luzak V, Wegat V, Doll D, Sodmann A, Bady E, Langlhofer G, Wachter B, Havlicek S, Gupta J, Horn E, Lüningschrör P, Villmann C, Polat B, Wischhusen J, Monoranu CM, Kuper J, Blum R. Gupta R, et al. Among authors: horn e. Cancer Gene Ther. 2024 Sep;31(9):1357-1379. doi: 10.1038/s41417-024-00809-0. Epub 2024 Jul 22. Cancer Gene Ther. 2024. PMID: 39039193 Free PMC article.
716 results