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Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism.
Jiang M, Porat-Shliom Y, Pei Z, Cheng Y, Xiang L, Sommers K, Li Q, Gillardon F, Hengerer B, Berlinicke C, Smith WW, Zack DJ, Poirier MA, Ross CA, Duan W. Jiang M, et al. Among authors: xiang l. J Neurochem. 2010 Jul;114(2):419-29. doi: 10.1111/j.1471-4159.2010.06752.x. Epub 2010 Apr 19. J Neurochem. 2010. PMID: 20412383 Free PMC article.
trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease.
Fu J, Jin J, Cichewicz RH, Hageman SA, Ellis TK, Xiang L, Peng Q, Jiang M, Arbez N, Hotaling K, Ross CA, Duan W. Fu J, et al. Among authors: xiang l. J Biol Chem. 2012 Jul 13;287(29):24460-72. doi: 10.1074/jbc.M112.382226. Epub 2012 May 30. J Biol Chem. 2012. PMID: 22648412 Free PMC article.
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Jiang M, et al. Among authors: xiang l. Nat Med. 2011 Dec 18;18(1):153-8. doi: 10.1038/nm.2558. Nat Med. 2011. PMID: 22179319 Free PMC article.
Rare and common genetic variants underlying the risk of Hirschsprung's disease.
Xiao J, Feng C, Zhu T, Zhang X, Chen X, Li Z, You J, Wang Q, Zhuansun D, Meng X, Wang J, Xiang L, Yu X, Zhou B, Tang W, Tou J, Wang Y, Yang H, Yu L, Liu Y, Jiang X, Ren H, Yu M, Chen Q, Yin Q, Liu X, Xu Z, Wu D, Yu D, Wu X, Yang J, Xiong B, Chen F, Hao X, Feng J. Xiao J, et al. Among authors: xiang l. Hum Mol Genet. 2025 Jan 16:ddae205. doi: 10.1093/hmg/ddae205. Online ahead of print. Hum Mol Genet. 2025. PMID: 39817569
A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets.
Li C, Li J, Gong B, Xu H, Guo Z, Xiang L, Zhang S, Sun Q, Zhao J, Zhang M, Tang YD, Leng C, Wu J, Wang Q, Peng J, Zhou G, Liu H, An T, Cai X, Tian ZJ, Zhang H. Li C, et al. Among authors: xiang l. Virulence. 2025 Dec;16(1):2451754. doi: 10.1080/21505594.2025.2451754. Epub 2025 Jan 12. Virulence. 2025. PMID: 39800863 Free PMC article.
3,494 results