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Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal.
Prazeres HJ, Rodrigues F, Figueiredo P, Naidenov P, Soares P, Bugalho MJ, Lacerda M, Campos B, Martins TC. Prazeres HJ, et al. Among authors: martins tc. Clin Endocrinol (Oxf). 2006 Jun;64(6):659-66. doi: 10.1111/j.1365-2265.2006.02524.x. Clin Endocrinol (Oxf). 2006. PMID: 16712668
In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp.
Prazeres H, Couto JP, Rodrigues F, Vinagre J, Torres J, Trovisco V, Martins TC, Sobrinho-Simões M, Soares P. Prazeres H, et al. Among authors: martins tc. Endocr Relat Cancer. 2011 Jul 1;18(4):401-12. doi: 10.1530/ERC-10-0258. Print 2011 Aug. Endocr Relat Cancer. 2011. PMID: 21551259 Clinical Trial.
74 results