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Synthesis of multivalent glycoconjugates containing the immunoactive LELTE peptide: effect of glycosylation on cellular activation and natural killing by human peripheral blood mononuclear cells.
Renaudet O, Krenek K, Bossu I, Dumy P, Kádek A, Adámek D, Vanek O, Kavan D, Gazák R, Sulc M, Bezouska K, Kren V. Renaudet O, et al. Among authors: vanek o. J Am Chem Soc. 2010 May 19;132(19):6800-8. doi: 10.1021/ja101296t. J Am Chem Soc. 2010. Retraction in: J Am Chem Soc. 2014 Jan 22;136(3):1156. doi: 10.1021/ja4081277 PMID: 20420392 Retracted.
Cooperation between subunits is essential for high-affinity binding of N-acetyl-D-hexosamines to dimeric soluble and dimeric cellular forms of human CD69.
Kavan D, Kubícková M, Bílý J, Vanek O, Hofbauerová K, Mrázek H, Rozbeský D, Bojarová P, Kren V, Zídek L, Sklenár V, Bezouska K. Kavan D, et al. Among authors: vanek o. Biochemistry. 2010 May 18;49(19):4060-7. doi: 10.1021/bi100181a. Biochemistry. 2010. Retraction in: Biochemistry. 2014 May 6;53(17):2864. doi: 10.1021/bi500367g PMID: 20369839 Retracted.
Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ killer lymphocytes upon dimerization via a hydrophilic flexible linker.
Kovalová A, Ledvina M, Saman D, Zyka D, Kubícková M, Zídek L, Sklenár V, Pompach P, Kavan D, Bílý J, Vanek O, Kubínková Z, Libigerová M, Ivanová L, Antolíková M, Mrázek H, Rozbeský D, Hofbauerová K, Kren V, Bezouska K. Kovalová A, et al. Among authors: vanek o. J Med Chem. 2010 May 27;53(10):4050-65. doi: 10.1021/jm100055b. J Med Chem. 2010. Retraction in: J Med Chem. 2014 Jun 26;57(12):5477. doi: 10.1021/jm5007726 PMID: 20433142 Retracted.
Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice.
Vanek O, Nálezková M, Kavan D, Borovicková I, Pompach P, Novák P, Kumar V, Vannucci L, Hudecek J, Hofbauerová K, Kopecký V Jr, Brynda J, Kolenko P, Dohnálek J, Kaderávek P, Chmelík J, Gorcík L, Zídek L, Sklenár V, Bezouska K. Vanek O, et al. FEBS J. 2008 Nov;275(22):5589-606. doi: 10.1111/j.1742-4658.2008.06683.x. FEBS J. 2008. PMID: 18959746 Free article.
Molecular architecture of mouse activating NKR-P1 receptors.
Kolenko P, Rozbeský D, Vaněk O, Kopecký V Jr, Hofbauerová K, Novák P, Pompach P, Hašek J, Skálová T, Bezouška K, Dohnálek J. Kolenko P, et al. Among authors: vanek o. J Struct Biol. 2011 Sep;175(3):434-41. doi: 10.1016/j.jsb.2011.05.001. Epub 2011 May 12. J Struct Biol. 2011. PMID: 21600988
The high-resolution structure of the extracellular domain of human CD69 using a novel polymer.
Kolenko P, Skálová T, Vanek O, Stepánková A, Dusková J, Hasek J, Bezouska K, Dohnálek J. Kolenko P, et al. Among authors: vanek o. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt 12):1258-60. doi: 10.1107/S1744309109043152. Epub 2009 Nov 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 20054122 Free PMC article.
52 results