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Colon cancer stem cells: promise of targeted therapy.
Todaro M, Francipane MG, Medema JP, Stassi G. Todaro M, et al. Among authors: medema jp. Gastroenterology. 2010 Jun;138(6):2151-62. doi: 10.1053/j.gastro.2009.12.063. Gastroenterology. 2010. PMID: 20420952 Review.
PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells.
Mangiapane LR, Nicotra A, Turdo A, Gaggianesi M, Bianca P, Di Franco S, Sardina DS, Veschi V, Signore M, Beyes S, Fagnocchi L, Fiori ME, Bongiorno MR, Lo Iacono M, Pillitteri I, Ganduscio G, Gulotta G, Medema JP, Zippo A, Todaro M, De Maria R, Stassi G. Mangiapane LR, et al. Among authors: medema jp. Gut. 2022 Jan;71(1):119-128. doi: 10.1136/gutjnl-2020-323553. Epub 2021 Jan 12. Gut. 2022. PMID: 33436496 Free PMC article.
IL-4-mediated drug resistance in colon cancer stem cells.
Todaro M, Perez Alea M, Scopelliti A, Medema JP, Stassi G. Todaro M, et al. Among authors: medema jp. Cell Cycle. 2008 Feb 1;7(3):309-13. doi: 10.4161/cc.7.3.5389. Epub 2007 Nov 30. Cell Cycle. 2008. PMID: 18235245 Review.
Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging.
Tirinato L, Liberale C, Di Franco S, Candeloro P, Benfante A, La Rocca R, Potze L, Marotta R, Ruffilli R, Rajamanickam VP, Malerba M, De Angelis F, Falqui A, Carbone E, Todaro M, Medema JP, Stassi G, Di Fabrizio E. Tirinato L, et al. Among authors: medema jp. Stem Cells. 2015 Jan;33(1):35-44. doi: 10.1002/stem.1837. Stem Cells. 2015. PMID: 25186497 Free PMC article.
Betulinic Acid Kills Colon Cancer Stem Cells.
Potze L, di Franco S, Kessler JH, Stassi G, Medema JP. Potze L, et al. Among authors: medema jp. Curr Stem Cell Res Ther. 2016;11(5):427-33. doi: 10.2174/1574888x11666151203223512. Curr Stem Cell Res Ther. 2016. PMID: 26647913
ΔNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis.
Di Franco S, Turdo A, Benfante A, Colorito ML, Gaggianesi M, Apuzzo T, Kandimalla R, Chinnici A, Barcaroli D, Mangiapane LR, Pistone G, Vieni S, Gulotta E, Dieli F, Medema JP, Stassi G, De Laurenzi V, Todaro M. Di Franco S, et al. Among authors: medema jp. Oncotarget. 2016 Aug 23;7(34):54157-54173. doi: 10.18632/oncotarget.11022. Oncotarget. 2016. PMID: 27494839 Free PMC article.
Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.
Linnekamp JF, Hooff SRV, Prasetyanti PR, Kandimalla R, Buikhuisen JY, Fessler E, Ramesh P, Lee KAST, Bochove GGW, de Jong JH, Cameron K, Leersum RV, Rodermond HM, Franitza M, Nürnberg P, Mangiapane LR, Wang X, Clevers H, Vermeulen L, Stassi G, Medema JP. Linnekamp JF, et al. Among authors: medema jp. Cell Death Differ. 2018 Mar;25(3):616-633. doi: 10.1038/s41418-017-0011-5. Epub 2018 Jan 5. Cell Death Differ. 2018. PMID: 29305587 Free PMC article.
Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.
Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L. Lenos KJ, et al. Among authors: medema jp. Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3. Nat Cell Biol. 2018. PMID: 30177776 Free PMC article.
255 results