Dowal L - Search Results

1

The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion.

Woronowicz K, Dilks JR, Rozenvayn N, Dowal L, Blair PS, Peters CG, Woronowicz L, Flaumenhaft R. Woronowicz K, et al. Among authors: dowal l. Biochemistry. 2010 Jun 1;49(21):4533-42. doi: 10.1021/bi100541t. Biochemistry. 2010. PMID: 20429610 Free PMC article.

2

Targeting platelet G-protein coupled receptors (GPCRs): looking beyond conventional GPCR antagonism.

Dowal L, Flaumenhaft R. Dowal L, et al. Curr Vasc Pharmacol. 2010 Mar;8(2):140-54. doi: 10.2174/157016110790886938. Curr Vasc Pharmacol. 2010. PMID: 19485898 Review.

3

Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1.

Dowal L, Sim DS, Dilks JR, Blair P, Beaudry S, Denker BM, Koukos G, Kuliopulos A, Flaumenhaft R. Dowal L, et al. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2951-6. doi: 10.1073/pnas.1014863108. Epub 2011 Jan 31. Proc Natl Acad Sci U S A. 2011. PMID: 21282664 Free PMC article.

4

Proteomic analysis of palmitoylated platelet proteins.

Dowal L, Yang W, Freeman MR, Steen H, Flaumenhaft R. Dowal L, et al. Blood. 2011 Sep 29;118(13):e62-73. doi: 10.1182/blood-2011-05-353078. Epub 2011 Aug 2. Blood. 2011. PMID: 21813449 Free PMC article.

5

Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor.

Dockendorff C, Aisiku O, Verplank L, Dilks JR, Smith DA, Gunnink SF, Dowal L, Negri J, Palmer M, Macpherson L, Schreiber SL, Flaumenhaft R. Dockendorff C, et al. Among authors: dowal l. ACS Med Chem Lett. 2012 Mar 8;3(3):232-237. doi: 10.1021/ml2002696. Epub 2012 Jan 30. ACS Med Chem Lett. 2012. PMID: 22408714 Free PMC article.

6

Protein kinase C phosphorylation of PLCβ1 regulates its cellular localization.

Aisiku O, Dowal L, Scarlata S. Aisiku O, et al. Among authors: dowal l. Arch Biochem Biophys. 2011 May 15;509(2):186-90. doi: 10.1016/j.abb.2011.02.006. Epub 2011 Feb 19. Arch Biochem Biophys. 2011. PMID: 21338571 Free PMC article.

7

Selective interaction of the C2 domains of phospholipase C-beta1 and -beta2 with activated Galphaq subunits: an alternative function for C2-signaling modules.

Wang T, Pentyala S, Elliott JT, Dowal L, Gupta E, Rebecchi MJ, Scarlata S. Wang T, et al. Among authors: dowal l. Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7843-6. doi: 10.1073/pnas.96.14.7843. Proc Natl Acad Sci U S A. 1999. PMID: 10393909 Free PMC article.

8

The use of green fluorescent proteins to view association between phospholipase C beta and G protein subunits in cells.

Scarlata S, Dowal L. Scarlata S, et al. Among authors: dowal l. Methods Mol Biol. 2004;237:223-32. doi: 10.1385/1-59259-430-1:223. Methods Mol Biol. 2004. PMID: 14501053 Review.

9

Determination of the contact energies between a regulator of G protein signaling and G protein subunits and phospholipase C beta 1.

Dowal L, Elliott J, Popov S, Wilkie TM, Scarlata S. Dowal L, et al. Biochemistry. 2001 Jan 16;40(2):414-21. doi: 10.1021/bi001923+. Biochemistry. 2001. PMID: 11148035

10

Stable association between G alpha(q) and phospholipase C beta 1 in living cells.

Dowal L, Provitera P, Scarlata S. Dowal L, et al. J Biol Chem. 2006 Aug 18;281(33):23999-4014. doi: 10.1074/jbc.M512330200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754659 Free article.

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