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Human TopBP1 ensures genome integrity during normal S phase.
Kim JE, McAvoy SA, Smith DI, Chen J. Kim JE, et al. Among authors: chen j. Mol Cell Biol. 2005 Dec;25(24):10907-15. doi: 10.1128/MCB.25.24.10907-10915.2005. Mol Cell Biol. 2005. PMID: 16314514 Free PMC article.
DBC1 is a negative regulator of SIRT1.
Kim JE, Chen J, Lou Z. Kim JE, et al. Among authors: chen j. Nature. 2008 Jan 31;451(7178):583-6. doi: 10.1038/nature06500. Nature. 2008. PMID: 18235501
p30 DBC is a potential regulator of tumorigenesis.
Kim JE, Chen J, Lou Z. Kim JE, et al. Among authors: chen j. Cell Cycle. 2009 Sep 15;8(18):2932-5. doi: 10.4161/cc.8.18.9473. Epub 2009 Sep 8. Cell Cycle. 2009. PMID: 19657230 Free PMC article. Review.
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