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Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors.
Pesonen S, Nokisalmi P, Escutenaire S, Särkioja M, Raki M, Cerullo V, Kangasniemi L, Laasonen L, Ribacka C, Guse K, Haavisto E, Oksanen M, Rajecki M, Helminen A, Ristimäki A, Karioja-Kallio A, Karli E, Kantola T, Bauerschmitz G, Kanerva A, Joensuu T, Hemminki A. Pesonen S, et al. Gene Ther. 2010 Jul;17(7):892-904. doi: 10.1038/gt.2010.17. Epub 2010 Mar 18. Gene Ther. 2010. PMID: 20237509
Oncolytic adenovirus based on serotype 3.
Hemminki O, Bauerschmitz G, Hemmi S, Lavilla-Alonso S, Diaconu I, Guse K, Koski A, Desmond RA, Lappalainen M, Kanerva A, Cerullo V, Pesonen S, Hemminki A. Hemminki O, et al. Cancer Gene Ther. 2011 Apr;18(4):288-96. doi: 10.1038/cgt.2010.79. Epub 2010 Dec 24. Cancer Gene Ther. 2011. PMID: 21183947 Free article.
Luciferase imaging for evaluation of oncolytic adenovirus replication in vivo.
Guse K, Dias JD, Bauerschmitz GJ, Hakkarainen T, Aavik E, Ranki T, Pisto T, Särkioja M, Desmond RA, Kanerva A, Hemminki A. Guse K, et al. Among authors: bauerschmitz gj. Gene Ther. 2007 Jun;14(11):902-11. doi: 10.1038/sj.gt.3302949. Epub 2007 Mar 22. Gene Ther. 2007. PMID: 17377596
Oncolytic adenoviruses kill breast cancer initiating CD44+CD24-/low cells.
Eriksson M, Guse K, Bauerschmitz G, Virkkunen P, Tarkkanen M, Tanner M, Hakkarainen T, Kanerva A, Desmond RA, Pesonen S, Hemminki A. Eriksson M, et al. Mol Ther. 2007 Dec;15(12):2088-93. doi: 10.1038/sj.mt.6300300. Epub 2007 Sep 11. Mol Ther. 2007. PMID: 17848962 Free article.
Adenoviruses with an αvβ integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases.
Lavilla-Alonso S, Bauerschmitz G, Abo-Ramadan U, Halavaara J, Escutenaire S, Diaconu I, Tatlisumak T, Kanerva A, Hemminki A, Pesonen S. Lavilla-Alonso S, et al. J Transl Med. 2010 Aug 23;8:80. doi: 10.1186/1479-5876-8-80. J Transl Med. 2010. PMID: 20727221 Free PMC article.
51 results