Edwards TA - Search Results

1

N-alkylated oligoamide alpha-helical proteomimetics.

Campbell F, Plante JP, Edwards TA, Warriner SL, Wilson AJ. Campbell F, et al. Among authors: edwards ta. Org Biomol Chem. 2010 May 21;8(10):2344-51. doi: 10.1039/c001164a. Epub 2010 Mar 18. Org Biomol Chem. 2010. PMID: 20448891

2

Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction.

Plante JP, Burnley T, Malkova B, Webb ME, Warriner SL, Edwards TA, Wilson AJ. Plante JP, et al. Among authors: edwards ta. Chem Commun (Camb). 2009 Sep 14;(34):5091-3. doi: 10.1039/b908207g. Epub 2009 Jun 24. Chem Commun (Camb). 2009. PMID: 20448956 Free PMC article.

3

Helix-mediated protein--protein interactions as targets for intervention using foldamers.

Edwards TA, Wilson AJ. Edwards TA, et al. Amino Acids. 2011 Aug;41(3):743-54. doi: 10.1007/s00726-011-0880-8. Epub 2011 Mar 17. Amino Acids. 2011. PMID: 21409387 Review.

4

2-O-alkylated para-benzamide α-helix mimetics: the role of scaffold curvature.

Azzarito V, Prabhakaran P, Bartlett AI, Murphy NS, Hardie MJ, Kilner CA, Edwards TA, Warriner SL, Wilson AJ. Azzarito V, et al. Among authors: edwards ta. Org Biomol Chem. 2012 Aug 28;10(32):6469-72. doi: 10.1039/c2ob26262b. Epub 2012 Jul 11. Org Biomol Chem. 2012. PMID: 22785578

5

Modeling of arylamide helix mimetics in the p53 peptide binding site of hDM2 suggests parallel and anti-parallel conformations are both stable.

Fuller JC, Jackson RM, Edwards TA, Wilson AJ, Shirts MR. Fuller JC, et al. Among authors: edwards ta. PLoS One. 2012;7(8):e43253. doi: 10.1371/journal.pone.0043253. Epub 2012 Aug 20. PLoS One. 2012. PMID: 22916232 Free PMC article.

6

Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide α-helix mimetics.

Long K, Edwards TA, Wilson AJ. Long K, et al. Among authors: edwards ta. Bioorg Med Chem. 2013 Jul 15;21(14):4034-40. doi: 10.1016/j.bmc.2012.09.053. Epub 2012 Oct 3. Bioorg Med Chem. 2013. PMID: 23117175 Free article.

7

Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction.

Burslem GM, Kyle HF, Breeze AL, Edwards TA, Nelson A, Warriner SL, Wilson AJ. Burslem GM, et al. Among authors: edwards ta. Chembiochem. 2014 May 26;15(8):1083-7. doi: 10.1002/cbic.201400009. Epub 2014 Apr 29. Chembiochem. 2014. PMID: 24782431 Free PMC article.

8

Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions.

Barnard A, Long K, Martin HL, Miles JA, Edwards TA, Tomlinson DC, Macdonald A, Wilson AJ. Barnard A, et al. Among authors: edwards ta. Angew Chem Int Ed Engl. 2015 Mar 2;54(10):2960-5. doi: 10.1002/anie.201410810. Epub 2015 Feb 4. Angew Chem Int Ed Engl. 2015. PMID: 25651514 Free PMC article.

9

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.

Kyle HF, Wickson KF, Stott J, Burslem GM, Breeze AL, Tiede C, Tomlinson DC, Warriner SL, Nelson A, Wilson AJ, Edwards TA. Kyle HF, et al. Among authors: edwards ta. Mol Biosyst. 2015 Oct;11(10):2738-49. doi: 10.1039/c5mb00284b. Mol Biosyst. 2015. PMID: 26135796 Free article.

10

Probing Protein Surfaces: QSAR Analysis with Helix Mimetics.

Azzarito V, Rowell P, Barnard A, Edwards TA, Macdonald A, Warriner SL, Wilson AJ. Azzarito V, et al. Among authors: edwards ta. Chembiochem. 2016 Apr 15;17(8):768-73. doi: 10.1002/cbic.201500504. Epub 2016 Jan 21. Chembiochem. 2016. PMID: 26690307 Free PMC article.

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