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p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.
Oncogene. 2010 Jul 8;29(27):3942-52. doi: 10.1038/onc.2010.145. Epub 2010 May 10.
Oncogene. 2010.
PMID: 20453878
Free article.
Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities.
Amstutz R, Wachtel M, Troxler H, Kleinert P, Ebauer M, Haneke T, Oehler-Jänne C, Fabbro D, Niggli FK, Schäfer BW.
Amstutz R, et al.
Cancer Res. 2008 May 15;68(10):3767-76. doi: 10.1158/0008-5472.CAN-07-2447.
Cancer Res. 2008.
PMID: 18483260
Free article.
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Tissue expression and actin binding of a novel N-terminal utrophin isoform.
Zuellig RA, Bornhauser BC, Amstutz R, Constantin B, Schaub MC.
Zuellig RA, et al. Among authors: amstutz r.
J Biomed Biotechnol. 2011;2011:904547. doi: 10.1155/2011/904547. Epub 2011 Nov 14.
J Biomed Biotechnol. 2011.
PMID: 22228988
Free PMC article.
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