Dennis MS - Search Results

1

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.

Brightbill HD, Jeet S, Lin Z, Yan D, Zhou M, Tan M, Nguyen A, Yeh S, Delarosa D, Leong SR, Wong T, Chen Y, Ultsch M, Luis E, Ramani SR, Jackman J, Gonzalez L, Dennis MS, Chuntharapai A, DeForge L, Meng YG, Xu M, Eigenbrot C, Lee WP, Refino CJ, Balazs M, Wu LC. Brightbill HD, et al. Among authors: dennis ms. J Clin Invest. 2010 Jun;120(6):2218-29. doi: 10.1172/JCI40141. Epub 2010 May 10. J Clin Invest. 2010. PMID: 20458139 Free PMC article.

2

Peptide exosite inhibitors of factor VIIa as anticoagulants.

Dennis MS, Eigenbrot C, Skelton NJ, Ultsch MH, Santell L, Dwyer MA, O'Connell MP, Lazarus RA. Dennis MS, et al. Nature. 2000 Mar 30;404(6777):465-70. doi: 10.1038/35006574. Nature. 2000. PMID: 10761907

3

The factor VII zymogen structure reveals reregistration of beta strands during activation.

Eigenbrot C, Kirchhofer D, Dennis MS, Santell L, Lazarus RA, Stamos J, Ultsch MH. Eigenbrot C, et al. Among authors: dennis ms. Structure. 2001 Jul 3;9(7):627-36. doi: 10.1016/s0969-2126(01)00624-4. Structure. 2001. PMID: 11470437 Free article.

4

A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors.

Roberge M, Santell L, Dennis MS, Eigenbrot C, Dwyer MA, Lazarus RA. Roberge M, et al. Among authors: dennis ms. Biochemistry. 2001 Aug 14;40(32):9522-31. doi: 10.1021/bi010592d. Biochemistry. 2001. PMID: 11583151

5

Albumin binding as a general strategy for improving the pharmacokinetics of proteins.

Dennis MS, Zhang M, Meng YG, Kadkhodayan M, Kirchhofer D, Combs D, Damico LA. Dennis MS, et al. J Biol Chem. 2002 Sep 20;277(38):35035-43. doi: 10.1074/jbc.M205854200. Epub 2002 Jul 15. J Biol Chem. 2002. PMID: 12119302 Free article.

6

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.

Lee CV, Liang WC, Dennis MS, Eigenbrot C, Sidhu SS, Fuh G. Lee CV, et al. Among authors: dennis ms. J Mol Biol. 2004 Jul 23;340(5):1073-93. doi: 10.1016/j.jmb.2004.05.051. J Mol Biol. 2004. PMID: 15236968

7

The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin.

Nguyen A, Reyes AE 2nd, Zhang M, McDonald P, Wong WL, Damico LA, Dennis MS. Nguyen A, et al. Among authors: dennis ms. Protein Eng Des Sel. 2006 Jul;19(7):291-7. doi: 10.1093/protein/gzl011. Epub 2006 Apr 18. Protein Eng Des Sel. 2006. PMID: 16621915

8

Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library.

Liang WC, Dennis MS, Stawicki S, Chanthery Y, Pan Q, Chen Y, Eigenbrot C, Yin J, Koch AW, Wu X, Ferrara N, Bagri A, Tessier-Lavigne M, Watts RJ, Wu Y. Liang WC, et al. Among authors: dennis ms. J Mol Biol. 2007 Feb 23;366(3):815-29. doi: 10.1016/j.jmb.2006.11.021. Epub 2006 Nov 10. J Mol Biol. 2007. PMID: 17196977

9

Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models.

Chen Y, Clark S, Wong T, Chen Y, Chen Y, Dennis MS, Luis E, Zhong F, Bheddah S, Koeppen H, Gogineni A, Ross S, Polakis P, Mallet W. Chen Y, et al. Among authors: dennis ms. Cancer Res. 2007 May 15;67(10):4924-32. doi: 10.1158/0008-5472.CAN-06-4512. Cancer Res. 2007. PMID: 17510422

10

Unveiling a glycation hot spot in a recombinant humanized monoclonal antibody.

Zhang B, Yang Y, Yuk I, Pai R, McKay P, Eigenbrot C, Dennis M, Katta V, Francissen KC. Zhang B, et al. Anal Chem. 2008 Apr 1;80(7):2379-90. doi: 10.1021/ac701810q. Epub 2008 Feb 29. Anal Chem. 2008. PMID: 18307322

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