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Page 1
Crystal structures of Aspergillus japonicus fructosyltransferase complex with donor/acceptor substrates reveal complete subsites in the active site for catalysis.
Chuankhayan P, Hsieh CY, Huang YC, Hsieh YY, Guan HH, Hsieh YC, Tien YC, Chen CD, Chiang CM, Chen CJ. Chuankhayan P, et al. Among authors: chen cd, chen cj. J Biol Chem. 2010 Jul 23;285(30):23251-64. doi: 10.1074/jbc.M110.113027. Epub 2010 May 13. J Biol Chem. 2010. PMID: 20466731 Free PMC article.
Crystal structures of complexes of the branched-chain aminotransferase from Deinococcus radiodurans with α-ketoisocaproate and L-glutamate suggest the radiation resistance of this enzyme for catalysis.
Chen CD, Lin CH, Chuankhayan P, Huang YC, Hsieh YC, Huang TF, Guan HH, Liu MY, Chang WC, Chen CJ. Chen CD, et al. Among authors: chen cj. J Bacteriol. 2012 Nov;194(22):6206-16. doi: 10.1128/JB.01659-12. Epub 2012 Sep 14. J Bacteriol. 2012. PMID: 22984263 Free PMC article.
Direct phase selection of initial phases from single-wavelength anomalous dispersion (SAD) for the improvement of electron density and ab initio structure determination.
Chen CD, Huang YC, Chiang HL, Hsieh YC, Guan HH, Chuankhayan P, Chen CJ. Chen CD, et al. Among authors: chen cj. Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2331-43. doi: 10.1107/S1399004714013868. Epub 2014 Aug 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25195747 Free PMC article.
Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1.
Zhang L, Zhang H, Wang TY, Li M, Chan AKN, Kang H, Foong LC, Liu Q, Pokharel SP, Mattson NM, Singh P, Elsayed Z, Kuang B, Wang X, Rosen ST, Chen J, Yang L, Chou TF, Su R, Chen CD. Zhang L, et al. Among authors: chen cd. Adv Sci (Weinh). 2024 Dec 23:e2404620. doi: 10.1002/advs.202404620. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39716856
Desipramine reverses remote memory deficits by activating calmodulin-CaMKII pathway in a UTX knockout mouse model of Kabuki syndrome.
Chen L, Li Y, Liu M, Lan Z, Zhang X, Yang X, Zhao Q, Wang S, Xu L, Zhou Y, Kuang Y, Suzuki T, Tabuchi K, Takahashi E, Zhou M, Chen CD, Xu T, Li W. Chen L, et al. Among authors: chen cd. Gen Psychiatr. 2024 Oct 29;37(5):e101430. doi: 10.1136/gpsych-2023-101430. eCollection 2024. Gen Psychiatr. 2024. PMID: 39493372 Free PMC article.
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Schultz SA, Liu L, Schultz AP, Fitzpatrick CD, Levin R, Bellier JP, Shirzadi Z, Joseph-Mathurin N, Chen CD, Benzinger TLS, Day GS, Farlow MR, Gordon BA, Hassenstab JJ, Jack CR Jr, Jucker M, Karch CM, Lee JH, Levin J, Perrin RJ, Schofield PR, Xiong C, Johnson KA, McDade E, Bateman RJ, Sperling RA, Selkoe DJ, Chhatwal JP; Dominantly Inherited Alzheimer Network. Schultz SA, et al. Among authors: chen cd. Lancet Neurol. 2024 Sep;23(9):913-924. doi: 10.1016/S1474-4422(24)00236-9. Epub 2024 Jul 26. Lancet Neurol. 2024. PMID: 39074479
Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease.
Farrell ME, Thibault EG, Becker JA, Price JC, Healy BC, Hanseeuw BJ, Buckley RF, Jacobs HIL, Schultz AP, Chen CD, Sperling RA, Johnson KA. Farrell ME, et al. Among authors: chen cd. Alzheimers Dement. 2024 Aug;20(8):5434-5449. doi: 10.1002/alz.14036. Epub 2024 Jul 10. Alzheimers Dement. 2024. PMID: 38988055 Free PMC article.
Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging.
Doering S, McCullough A, Gordon BA, Chen CD, McKay N, Hobbs D, Keefe S, Flores S, Scott J, Smith H, Jarman S, Jackson K, Hornbeck RC, Ances BM, Xiong C, Aschenbrenner AJ, Hassenstab J, Cruchaga C, Daniels A, Bateman RJ; Dominantly Inherited Alzheimer Network (DIAN) Investigators; Morris JC, Benzinger TLS. Doering S, et al. Among authors: chen cd. EBioMedicine. 2024 May;103:105080. doi: 10.1016/j.ebiom.2024.105080. Epub 2024 Mar 28. EBioMedicine. 2024. PMID: 38552342 Free PMC article.
Disease staging of Alzheimer's disease using a CSF-based biomarker model.
Salvadó G, Horie K, Barthélemy NR, Vogel JW, Pichet Binette A, Chen CD, Aschenbrenner AJ, Gordon BA, Benzinger TLS, Holtzman DM, Morris JC, Palmqvist S, Stomrud E, Janelidze S, Ossenkoppele R, Schindler SE, Bateman RJ, Hansson O. Salvadó G, et al. Among authors: chen cd. Nat Aging. 2024 May;4(5):694-708. doi: 10.1038/s43587-024-00599-y. Epub 2024 Mar 21. Nat Aging. 2024. PMID: 38514824 Free PMC article.
420 results