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Imatinib as a potential antiresorptive therapy for bone disease.
Dewar AL, Farrugia AN, Condina MR, Bik To L, Hughes TP, Vernon-Roberts B, Zannettino AC. Dewar AL, et al. Among authors: zannettino ac. Blood. 2006 Jun 1;107(11):4334-7. doi: 10.1182/blood-2005-09-3568. Epub 2006 Jan 31. Blood. 2006. PMID: 16449525 Free article.
OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib.
White DL, Saunders VA, Dang P, Engler J, Zannettino AC, Cambareri AC, Quinn SR, Manley PW, Hughes TP. White DL, et al. Among authors: zannettino ac. Blood. 2006 Jul 15;108(2):697-704. doi: 10.1182/blood-2005-11-4687. Epub 2006 Apr 4. Blood. 2006. PMID: 16597591 Free article.
Long-term imatinib therapy promotes bone formation in CML patients.
Fitter S, Dewar AL, Kostakis P, To LB, Hughes TP, Roberts MM, Lynch K, Vernon-Roberts B, Zannettino AC. Fitter S, et al. Among authors: zannettino ac. Blood. 2008 Mar 1;111(5):2538-47. doi: 10.1182/blood-2007-07-104281. Epub 2007 Nov 27. Blood. 2008. PMID: 18042796 Free article.
Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues.
Gronthos S, McCarty R, Mrozik K, Fitter S, Paton S, Menicanin D, Itescu S, Bartold PM, Xian C, Zannettino AC. Gronthos S, et al. Among authors: zannettino ac. Stem Cells Dev. 2009 Nov;18(9):1253-62. doi: 10.1089/scd.2008.0400. Stem Cells Dev. 2009. PMID: 19327008
222 results