Vassilopoulos A - Search Results

1

Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53.

Fishler T, Li YY, Wang RH, Kim HS, Sengupta K, Vassilopoulos A, Lahusen T, Xu X, Lee MH, Liu Q, Elledge SJ, Ried T, Deng CX. Fishler T, et al. Among authors: vassilopoulos a. Oncogene. 2010 Jul 15;29(28):4007-17. doi: 10.1038/onc.2010.163. Epub 2010 May 17. Oncogene. 2010. PMID: 20473325 Free PMC article.

2

A critical role of CD29 and CD49f in mediating metastasis for cancer-initiating cells isolated from a Brca1-associated mouse model of breast cancer.

Vassilopoulos A, Chisholm C, Lahusen T, Zheng H, Deng CX. Vassilopoulos A, et al. Oncogene. 2014 Nov 20;33(47):5477-82. doi: 10.1038/onc.2013.516. Epub 2013 Dec 9. Oncogene. 2014. PMID: 24317509

3

WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis.

Vassilopoulos A, Tominaga Y, Kim HS, Lahusen T, Li B, Yu H, Gius D, Deng CX. Vassilopoulos A, et al. Oncogene. 2015 Jun 4;34(23):3023-35. doi: 10.1038/onc.2014.239. Epub 2014 Aug 4. Oncogene. 2015. PMID: 25088202 Free PMC article.

4

BRCA1 affects global DNA methylation through regulation of DNMT1.

Shukla V, Coumoul X, Lahusen T, Wang RH, Xu X, Vassilopoulos A, Xiao C, Lee MH, Man YG, Ouchi M, Ouchi T, Deng CX. Shukla V, et al. Among authors: vassilopoulos a. Cell Res. 2010 Nov;20(11):1201-15. doi: 10.1038/cr.2010.128. Epub 2010 Sep 7. Cell Res. 2010. PMID: 20820192 Free PMC article.

5

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.

Kim HS, Vassilopoulos A, Wang RH, Lahusen T, Xiao Z, Xu X, Li C, Veenstra TD, Li B, Yu H, Ji J, Wang XW, Park SH, Cha YI, Gius D, Deng CX. Kim HS, et al. Among authors: vassilopoulos a. Cancer Cell. 2011 Oct 18;20(4):487-99. doi: 10.1016/j.ccr.2011.09.004. Cancer Cell. 2011. PMID: 22014574 Free PMC article.

6

Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.

Kim HS, Xiao C, Wang RH, Lahusen T, Xu X, Vassilopoulos A, Vazquez-Ortiz G, Jeong WI, Park O, Ki SH, Gao B, Deng CX. Kim HS, et al. Among authors: vassilopoulos a. Cell Metab. 2010 Sep 8;12(3):224-36. doi: 10.1016/j.cmet.2010.06.009. Cell Metab. 2010. PMID: 20816089 Free PMC article.

7

Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors.

Vassilopoulos A, Xiao C, Chisholm C, Chen W, Xu X, Lahusen TJ, Bewley C, Deng CX. Vassilopoulos A, et al. J Biol Chem. 2014 Aug 29;289(35):24202-14. doi: 10.1074/jbc.M114.567552. Epub 2014 Jul 8. J Biol Chem. 2014. PMID: 25006250 Free PMC article.

8

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.

Wang RH, Zheng Y, Kim HS, Xu X, Cao L, Luhasen T, Lee MH, Xiao C, Vassilopoulos A, Chen W, Gardner K, Man YG, Hung MC, Finkel T, Deng CX. Wang RH, et al. Among authors: vassilopoulos a. Mol Cell. 2008 Oct 10;32(1):11-20. doi: 10.1016/j.molcel.2008.09.011. Mol Cell. 2008. PMID: 18851829 Free PMC article.

9

Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells.

Vassilopoulos A, Wang RH, Petrovas C, Ambrozak D, Koup R, Deng CX. Vassilopoulos A, et al. Int J Biol Sci. 2008 May 4;4(3):133-42. doi: 10.7150/ijbs.4.133. Int J Biol Sci. 2008. PMID: 18461147 Free PMC article.

10

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.

Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, van der Meer R, Nguyen P, Savage J, Owens KM, Vassilopoulos A, Ozden O, Park SH, Singh KK, Abdulkadir SA, Spitz DR, Deng CX, Gius D. Kim HS, et al. Among authors: vassilopoulos a. Cancer Cell. 2010 Jan 19;17(1):41-52. doi: 10.1016/j.ccr.2009.11.023. Cancer Cell. 2010. PMID: 20129246 Free PMC article.

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