Ou TM - Search Results

1

Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives.

Wang XD, Ou TM, Lu YJ, Li Z, Xu Z, Xi C, Tan JH, Huang SL, An LK, Li D, Gu LQ, Huang ZS. Wang XD, et al. Among authors: ou tm. J Med Chem. 2010 Jun 10;53(11):4390-8. doi: 10.1021/jm100445e. J Med Chem. 2010. PMID: 20481493

2

Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.

Zhou JL, Lu YJ, Ou TM, Zhou JM, Huang ZS, Zhu XF, Du CJ, Bu XZ, Ma L, Gu LQ, Li YM, Chan AS. Zhou JL, et al. Among authors: ou tm. J Med Chem. 2005 Nov 17;48(23):7315-21. doi: 10.1021/jm050041b. J Med Chem. 2005. PMID: 16279791

3

Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.

Ou TM, Lu YJ, Zhang C, Huang ZS, Wang XD, Tan JH, Chen Y, Ma DL, Wong KY, Tang JC, Chan AS, Gu LQ. Ou TM, et al. J Med Chem. 2007 Apr 5;50(7):1465-74. doi: 10.1021/jm0610088. Epub 2007 Mar 9. J Med Chem. 2007. PMID: 17346034

4

9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.

Zhang WJ, Ou TM, Lu YJ, Huang YY, Wu WB, Huang ZS, Zhou JL, Wong KY, Gu LQ. Zhang WJ, et al. Among authors: ou tm. Bioorg Med Chem. 2007 Aug 15;15(16):5493-501. doi: 10.1016/j.bmc.2007.05.050. Epub 2007 May 25. Bioorg Med Chem. 2007. PMID: 17574421

5

G-quadruplexes: targets in anticancer drug design.

Ou TM, Lu YJ, Tan JH, Huang ZS, Wong KY, Gu LQ. Ou TM, et al. ChemMedChem. 2008 May;3(5):690-713. doi: 10.1002/cmdc.200700300. ChemMedChem. 2008. PMID: 18236491 Review.

6

9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.

Ma Y, Ou TM, Hou JQ, Lu YJ, Tan JH, Gu LQ, Huang ZS. Ma Y, et al. Among authors: ou tm. Bioorg Med Chem. 2008 Aug 15;16(16):7582-91. doi: 10.1016/j.bmc.2008.07.029. Epub 2008 Jul 18. Bioorg Med Chem. 2008. PMID: 18674916

7

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ. Lu YJ, et al. Among authors: ou tm. J Med Chem. 2008 Oct 23;51(20):6381-92. doi: 10.1021/jm800497p. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821749

8

Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.

Tan JH, Ou TM, Hou JQ, Lu YJ, Huang SL, Luo HB, Wu JY, Huang ZS, Wong KY, Gu LQ. Tan JH, et al. Among authors: ou tm. J Med Chem. 2009 May 14;52(9):2825-35. doi: 10.1021/jm801600m. J Med Chem. 2009. PMID: 19354252

9

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.

Ma Y, Ou TM, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS. Ma Y, et al. Among authors: ou tm. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3414-7. doi: 10.1016/j.bmcl.2009.05.030. Epub 2009 May 14. Bioorg Med Chem Lett. 2009. PMID: 19477640

10

Synthesis and antimultidrug resistance evaluation of icariin and its derivatives.

Liu DF, Li YP, Ou TM, Huang SL, Gu LQ, Huang M, Huang ZS. Liu DF, et al. Among authors: ou tm. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4237-40. doi: 10.1016/j.bmcl.2009.05.103. Epub 2009 May 30. Bioorg Med Chem Lett. 2009. PMID: 19523827

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