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The transcription factor Sox2 is required for osteoblast self-renewal.
Basu-Roy U, Ambrosetti D, Favaro R, Nicolis SK, Mansukhani A, Basilico C. Basu-Roy U, et al. Among authors: mansukhani a. Cell Death Differ. 2010 Aug;17(8):1345-53. doi: 10.1038/cdd.2010.57. Epub 2010 May 21. Cell Death Differ. 2010. PMID: 20489730 Free PMC article.
Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.
Seo E, Basu-Roy U, Zavadil J, Basilico C, Mansukhani A. Seo E, et al. Among authors: mansukhani a. Mol Cell Biol. 2011 Nov;31(22):4593-608. doi: 10.1128/MCB.05798-11. Epub 2011 Sep 19. Mol Cell Biol. 2011. PMID: 21930787 Free PMC article.
Basu-Roy et al., Cell Death Differ. 17:1345-1353, 2010; A. Mansukhani, D. Ambrosetti, G. Holmes, L. Cornivelli, and C. Basilico, J. Cell Biol. 168:1065-1076, 2005). ...Constitutive expression of the Polycomb complex member BMI-1 can bypass the Sox2 requirement for s …
Basu-Roy et al., Cell Death Differ. 17:1345-1353, 2010; A. Mansukhani, D. Ambrosetti, G. Holmes, L. Cornivelli, and C. Basilic …
Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas.
Basu-Roy U, Seo E, Ramanathapuram L, Rapp TB, Perry JA, Orkin SH, Mansukhani A, Basilico C. Basu-Roy U, et al. Among authors: mansukhani a. Oncogene. 2012 May 3;31(18):2270-82. doi: 10.1038/onc.2011.405. Epub 2011 Sep 19. Oncogene. 2012. PMID: 21927024 Free PMC article.
p21(WAF1/CIP1) acts as a brake in osteoblast differentiation.
Bellosta P, Masramon L, Mansukhani A, Basilico C. Bellosta P, et al. Among authors: mansukhani a. J Bone Miner Res. 2003 May;18(5):818-26. doi: 10.1359/jbmr.2003.18.5.818. J Bone Miner Res. 2003. PMID: 12733720 Free article.
Perspectives on cancer stem cells in osteosarcoma.
Basu-Roy U, Basilico C, Mansukhani A. Basu-Roy U, et al. Among authors: mansukhani a. Cancer Lett. 2013 Sep 10;338(1):158-67. doi: 10.1016/j.canlet.2012.05.028. Epub 2012 May 29. Cancer Lett. 2013. PMID: 22659734 Free PMC article. Review.
53 results