De Bosscher K - Search Results

1

Targeting inflammation using selective glucocorticoid receptor modulators.

De Bosscher K, Haegeman G, Elewaut D. De Bosscher K, et al. Curr Opin Pharmacol. 2010 Aug;10(4):497-504. doi: 10.1016/j.coph.2010.04.007. Epub 2010 May 20. Curr Opin Pharmacol. 2010. PMID: 20493772 Review.

2

Compound A attenuates proinflammatory cytokine-induced endoplasmic reticulum stress in beta cells and displays beneficial therapeutic effects in a mouse model of autoimmune diabetes.

Andreone L, Fuertes F, Sétula C, Barcala Tabarrozzi AE, Orellano MS, Dewey RA, Bottino R, De Bosscher K, Perone MJ. Andreone L, et al. Among authors: de bosscher k. Cell Mol Life Sci. 2022 Nov 12;79(12):587. doi: 10.1007/s00018-022-04615-5. Cell Mol Life Sci. 2022. PMID: 36370223

3

Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation.

De Bosscher K, Schmitz ML, Vanden Berghe W, Plaisance S, Fiers W, Haegeman G. De Bosscher K, et al. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13504-9. doi: 10.1073/pnas.94.25.13504. Proc Natl Acad Sci U S A. 1997. PMID: 9391055 Free PMC article.

4

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. J Biol Chem. 1998 Feb 6;273(6):3285-90. doi: 10.1074/jbc.273.6.3285. J Biol Chem. 1998. PMID: 9452444 Free article.

5

Cross-talk between steroids and NF-kappa B: what language?

Dumont A, Hehner SP, Schmitz ML, Gustafsson JA, Lidén J, Okret S, van der Saag PT, Wissink S, van der Burg B, Herrlich P, Haegeman G, De Bosscher K, Fiers W. Dumont A, et al. Among authors: de bosscher k. Trends Biochem Sci. 1998 Jul;23(7):233-5. doi: 10.1016/s0968-0004(98)01212-2. Trends Biochem Sci. 1998. PMID: 9697408 Review. No abstract available.

6

Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-kappaB-dependent mechanism.

Vanden Berghe W, Francesconi E, De Bosscher K, Resche-Rigon M, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. Mol Pharmacol. 1999 Oct;56(4):797-806. Mol Pharmacol. 1999. PMID: 10496964

7

Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1.

Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B. Delerive P, et al. Among authors: de bosscher k. J Biol Chem. 1999 Nov 5;274(45):32048-54. doi: 10.1074/jbc.274.45.32048. J Biol Chem. 1999. PMID: 10542237 Free article.

8

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. J Biol Chem. 1999 Nov 5;274(45):32091-8. doi: 10.1074/jbc.274.45.32091. J Biol Chem. 1999. PMID: 10542243 Free article.

9

Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell.

De Bosscher K, Vanden Berghe W, Vermeulen L, Plaisance S, Boone E, Haegeman G. De Bosscher K, et al. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):3919-24. doi: 10.1073/pnas.97.8.3919. Proc Natl Acad Sci U S A. 2000. PMID: 10760263 Free PMC article.

10

Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors.

De Bosscher K, Vanden Berghe W, Haegeman G. De Bosscher K, et al. J Neuroimmunol. 2000 Sep 1;109(1):16-22. doi: 10.1016/s0165-5728(00)00297-6. J Neuroimmunol. 2000. PMID: 10969176 Review.

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