Haegeman G - Search Results

1

Targeting inflammation using selective glucocorticoid receptor modulators.

De Bosscher K, Haegeman G, Elewaut D. De Bosscher K, et al. Among authors: haegeman g. Curr Opin Pharmacol. 2010 Aug;10(4):497-504. doi: 10.1016/j.coph.2010.04.007. Epub 2010 May 20. Curr Opin Pharmacol. 2010. PMID: 20493772 Review.

2

The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression.

De Bosscher K, Vanden Berghe W, Haegeman G. De Bosscher K, et al. Among authors: haegeman g. Endocr Rev. 2003 Aug;24(4):488-522. doi: 10.1210/er.2002-0006. Endocr Rev. 2003. PMID: 12920152 Review.

3

A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis.

Dewint P, Gossye V, De Bosscher K, Vanden Berghe W, Van Beneden K, Deforce D, Van Calenbergh S, Müller-Ladner U, Vander Cruyssen B, Verbruggen G, Haegeman G, Elewaut D. Dewint P, et al. Among authors: haegeman g. J Immunol. 2008 Feb 15;180(4):2608-15. doi: 10.4049/jimmunol.180.4.2608. J Immunol. 2008. PMID: 18250472

4

Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems.

De Bosscher K, Van Craenenbroeck K, Meijer OC, Haegeman G. De Bosscher K, et al. Among authors: haegeman g. Eur J Pharmacol. 2008 Apr 7;583(2-3):290-302. doi: 10.1016/j.ejphar.2007.11.076. Epub 2008 Jan 31. Eur J Pharmacol. 2008. PMID: 18289525 Review.

5

Minireview: latest perspectives on antiinflammatory actions of glucocorticoids.

De Bosscher K, Haegeman G. De Bosscher K, et al. Among authors: haegeman g. Mol Endocrinol. 2009 Mar;23(3):281-91. doi: 10.1210/me.2008-0283. Epub 2008 Dec 18. Mol Endocrinol. 2009. PMID: 19095768 Free PMC article. Review.

6

Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: possible partners in the combat against inflammation.

Beck IM, Vanden Berghe W, Gerlo S, Bougarne N, Vermeulen L, De Bosscher K, Haegeman G. Beck IM, et al. Among authors: haegeman g. Biochem Pharmacol. 2009 Apr 1;77(7):1194-205. doi: 10.1016/j.bcp.2008.12.008. Epub 2008 Dec 27. Biochem Pharmacol. 2009. PMID: 19150610

7

PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.

Bougarne N, Paumelle R, Caron S, Hennuyer N, Mansouri R, Gervois P, Staels B, Haegeman G, De Bosscher K. Bougarne N, et al. Among authors: haegeman g. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7397-402. doi: 10.1073/pnas.0806742106. Epub 2009 Apr 17. Proc Natl Acad Sci U S A. 2009. PMID: 19376972 Free PMC article.

8

Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts.

Gossye V, Elewaut D, Bougarne N, Bracke D, Van Calenbergh S, Haegeman G, De Bosscher K. Gossye V, et al. Among authors: haegeman g. Arthritis Rheum. 2009 Nov;60(11):3241-50. doi: 10.1002/art.24963. Arthritis Rheum. 2009. PMID: 19877072 Free article.

9

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases.

Beck IM, Vanden Berghe W, Vermeulen L, Yamamoto KR, Haegeman G, De Bosscher K. Beck IM, et al. Among authors: haegeman g. Endocr Rev. 2009 Dec;30(7):830-82. doi: 10.1210/er.2009-0013. Epub 2009 Nov 4. Endocr Rev. 2009. PMID: 19890091 Free PMC article. Review.

10

Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis.

van Loo G, Sze M, Bougarne N, Praet J, Mc Guire C, Ullrich A, Haegeman G, Prinz M, Beyaert R, De Bosscher K. van Loo G, et al. Among authors: haegeman g. Mol Endocrinol. 2010 Feb;24(2):310-22. doi: 10.1210/me.2009-0236. Epub 2009 Dec 4. Mol Endocrinol. 2010. PMID: 19965930 Free PMC article.

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