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655 results

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Page 1
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, Sun HC, Pitz KJ, Rock JM, Zhang L, Davis GD, Rebar EJ, Cheeseman IM, Yamamoto KR, Sabatini DM, Jaenisch R, Gregory PD, Urnov FD. DeKelver RC, et al. Among authors: jaenisch r. Genome Res. 2010 Aug;20(8):1133-42. doi: 10.1101/gr.106773.110. Epub 2010 May 27. Genome Res. 2010. PMID: 20508142 Free PMC article.
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R. Hockemeyer D, et al. Among authors: jaenisch r. Nat Biotechnol. 2009 Sep;27(9):851-7. doi: 10.1038/nbt.1562. Epub 2009 Aug 13. Nat Biotechnol. 2009. PMID: 19680244 Free PMC article.
Gene targeting in human pluripotent cells.
Hockemeyer D, Jaenisch R. Hockemeyer D, et al. Among authors: jaenisch r. Cold Spring Harb Symp Quant Biol. 2010;75:201-9. doi: 10.1101/sqb.2010.75.021. Epub 2011 Jan 5. Cold Spring Harb Symp Quant Biol. 2010. PMID: 21209393 Review.
Genetic engineering of human pluripotent cells using TALE nucleases.
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R. Hockemeyer D, et al. Among authors: jaenisch r. Nat Biotechnol. 2011 Jul 7;29(8):731-4. doi: 10.1038/nbt.1927. Nat Biotechnol. 2011. PMID: 21738127 Free PMC article.
Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells.
Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, Jaenisch R, Hockemeyer D. Forster R, et al. Among authors: jaenisch r. Stem Cell Reports. 2014 Jun 3;2(6):838-52. doi: 10.1016/j.stemcr.2014.05.001. eCollection 2014 Jun 3. Stem Cell Reports. 2014. PMID: 24936470 Free PMC article.
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, Urnov FD, Rebar EJ, Gregory PD, Zhang HS, Jaenisch R. Soldner F, et al. Among authors: jaenisch r. Cell. 2011 Jul 22;146(2):318-31. doi: 10.1016/j.cell.2011.06.019. Epub 2011 Jul 14. Cell. 2011. PMID: 21757228 Free PMC article.
Induced Pluripotent Stem Cells Meet Genome Editing.
Hockemeyer D, Jaenisch R. Hockemeyer D, et al. Among authors: jaenisch r. Cell Stem Cell. 2016 May 5;18(5):573-86. doi: 10.1016/j.stem.2016.04.013. Cell Stem Cell. 2016. PMID: 27152442 Free PMC article. Review.
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors.
Torikai H, Reik A, Soldner F, Warren EH, Yuen C, Zhou Y, Crossland DL, Huls H, Littman N, Zhang Z, Tykodi SS, Kebriaei P, Lee DA, Miller JC, Rebar EJ, Holmes MC, Jaenisch R, Champlin RE, Gregory PD, Cooper LJ. Torikai H, et al. Among authors: jaenisch r. Blood. 2013 Aug 22;122(8):1341-9. doi: 10.1182/blood-2013-03-478255. Epub 2013 Jun 5. Blood. 2013. PMID: 23741009 Free PMC article.
655 results