Nakahara T - Search Results

1

Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs.

Iwasa T, Okamoto I, Takezawa K, Yamanaka K, Nakahara T, Kita A, Koutoku H, Sasamata M, Hatashita E, Yamada Y, Kuwata K, Fukuoka M, Nakagawa K. Iwasa T, et al. Among authors: nakahara t. Br J Cancer. 2010 Jun 29;103(1):36-42. doi: 10.1038/sj.bjc.6605713. Epub 2010 Jun 1. Br J Cancer. 2010. PMID: 20517311 Free PMC article.

2

Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines.

Iwasa T, Okamoto I, Suzuki M, Nakahara T, Yamanaka K, Hatashita E, Yamada Y, Fukuoka M, Ono K, Nakagawa K. Iwasa T, et al. Among authors: nakahara t. Clin Cancer Res. 2008 Oct 15;14(20):6496-504. doi: 10.1158/1078-0432.CCR-08-0468. Clin Cancer Res. 2008. PMID: 18927289

3

Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models.

Nakahara T, Kita A, Yamanaka K, Mori M, Amino N, Takeuchi M, Tominaga F, Kinoyama I, Matsuhisa A, Kudou M, Sasamata M. Nakahara T, et al. Cancer Sci. 2011 Mar;102(3):614-21. doi: 10.1111/j.1349-7006.2010.01834.x. Epub 2011 Jan 12. Cancer Sci. 2011. PMID: 21205082 Free article.

4

YM155, a novel survivin suppressant, enhances taxane-induced apoptosis and tumor regression in a human Calu 6 lung cancer xenograft model.

Nakahara T, Yamanaka K, Hatakeyama S, Kita A, Takeuchi M, Kinoyama I, Matsuhisa A, Nakano K, Shishido T, Koutoku H, Sasamata M. Nakahara T, et al. Anticancer Drugs. 2011 Jun;22(5):454-62. doi: 10.1097/CAD.0b013e328344ac68. Anticancer Drugs. 2011. PMID: 21389848

5

Antitumor activity of YM155, a selective small-molecule survivin suppressant, alone and in combination with docetaxel in human malignant melanoma models.

Yamanaka K, Nakahara T, Yamauchi T, Kita A, Takeuchi M, Kiyonaga F, Kaneko N, Sasamata M. Yamanaka K, et al. Among authors: nakahara t. Clin Cancer Res. 2011 Aug 15;17(16):5423-31. doi: 10.1158/1078-0432.CCR-10-3410. Epub 2011 Jul 7. Clin Cancer Res. 2011. PMID: 21737502

6

YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.

Nakahara T, Kita A, Yamanaka K, Mori M, Amino N, Takeuchi M, Tominaga F, Hatakeyama S, Kinoyama I, Matsuhisa A, Kudoh M, Sasamata M. Nakahara T, et al. Cancer Res. 2007 Sep 1;67(17):8014-21. doi: 10.1158/0008-5472.CAN-07-1343. Cancer Res. 2007. PMID: 17804712

7

Antitumor effects of YM155, a novel survivin suppressant, against human aggressive non-Hodgkin lymphoma.

Kita A, Nakahara T, Yamanaka K, Nakano K, Nakata M, Mori M, Kaneko N, Koutoku H, Izumisawa N, Sasamata M. Kita A, et al. Among authors: nakahara t. Leuk Res. 2011 Jun;35(6):787-92. doi: 10.1016/j.leukres.2010.11.016. Epub 2011 Jan 14. Leuk Res. 2011. PMID: 21237508

8

YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer.

Yamanaka K, Nakata M, Kaneko N, Fushiki H, Kita A, Nakahara T, Koutoku H, Sasamata M. Yamanaka K, et al. Among authors: nakahara t. Int J Oncol. 2011 Sep;39(3):569-75. doi: 10.3892/ijo.2011.1077. Epub 2011 Jun 14. Int J Oncol. 2011. PMID: 21674125

9

Interleukin enhancer-binding factor 3/NF110 is a target of YM155, a suppressant of survivin.

Nakamura N, Yamauchi T, Hiramoto M, Yuri M, Naito M, Takeuchi M, Yamanaka K, Kita A, Nakahara T, Kinoyama I, Matsuhisa A, Kaneko N, Koutoku H, Sasamata M, Yokota H, Kawabata S, Furuichi K. Nakamura N, et al. Among authors: nakahara t. Mol Cell Proteomics. 2012 Jul;11(7):M111.013243. doi: 10.1074/mcp.M111.013243. Epub 2012 Mar 22. Mol Cell Proteomics. 2012. PMID: 22442257 Free PMC article.

10

Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression.

Yamauchi T, Nakamura N, Hiramoto M, Yuri M, Yokota H, Naitou M, Takeuchi M, Yamanaka K, Kita A, Nakahara T, Kinoyama I, Matsuhisa A, Kaneko N, Koutoku H, Sasamata M, Kobori M, Katou M, Tawara S, Kawabata S, Furuichi K. Yamauchi T, et al. Among authors: nakahara t. Biochem Biophys Res Commun. 2012 Sep 7;425(4):711-6. doi: 10.1016/j.bbrc.2012.07.103. Epub 2012 Jul 27. Biochem Biophys Res Commun. 2012. PMID: 22842455

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