Kissel T - Search Results

1

Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity.

Merkel OM, Mintzer MA, Librizzi D, Samsonova O, Dicke T, Sproat B, Garn H, Barth PJ, Simanek EE, Kissel T. Merkel OM, et al. Among authors: kissel t. Mol Pharm. 2010 Aug 2;7(4):969-83. doi: 10.1021/mp100101s. Mol Pharm. 2010. PMID: 20524664 Free PMC article.

2

Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance.

Merkel OM, Beyerle A, Librizzi D, Pfestroff A, Behr TM, Sproat B, Barth PJ, Kissel T. Merkel OM, et al. Among authors: kissel t. Mol Pharm. 2009 Jul-Aug;6(4):1246-60. doi: 10.1021/mp900107v. Mol Pharm. 2009. PMID: 19606864

3

Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity.

Merkel OM, Mintzer MA, Sitterberg J, Bakowsky U, Simanek EE, Kissel T. Merkel OM, et al. Among authors: kissel t. Bioconjug Chem. 2009 Sep;20(9):1799-806. doi: 10.1021/bc900243r. Bioconjug Chem. 2009. PMID: 19708683 Free PMC article.

4

Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems.

Merkel OM, Zheng M, Mintzer MA, Pavan GM, Librizzi D, Maly M, Höffken H, Danani A, Simanek EE, Kissel T. Merkel OM, et al. Among authors: kissel t. J Control Release. 2011 Jul 15;153(1):23-33. doi: 10.1016/j.jconrel.2011.02.016. Epub 2011 Feb 20. J Control Release. 2011. PMID: 21342661 Free PMC article.

5

Biophysical characterization of hyper-branched polyethylenimine-graft-polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery.

Liu Y, Samsonova O, Sproat B, Merkel O, Kissel T. Liu Y, et al. Among authors: kissel t. J Control Release. 2011 Aug 10;153(3):262-8. doi: 10.1016/j.jconrel.2011.04.017. Epub 2011 Apr 23. J Control Release. 2011. PMID: 21549166

6

Amphiphilic and biodegradable hy-PEI-g-PCL-b-PEG copolymers efficiently mediate transgene expression depending on their graft density.

Zheng M, Liu Y, Samsonova O, Endres T, Merkel O, Kissel T. Zheng M, et al. Among authors: kissel t. Int J Pharm. 2012 May 1;427(1):80-7. doi: 10.1016/j.ijpharm.2011.05.017. Epub 2011 May 12. Int J Pharm. 2012. PMID: 21600970

7

Nonviral pulmonary delivery of siRNA.

Merkel OM, Kissel T. Merkel OM, et al. Among authors: kissel t. Acc Chem Res. 2012 Jul 17;45(7):961-70. doi: 10.1021/ar200110p. Epub 2011 Sep 9. Acc Chem Res. 2012. PMID: 21905687

8

Pulmonary gene delivery using polymeric nonviral vectors.

Merkel OM, Zheng M, Debus H, Kissel T. Merkel OM, et al. Among authors: kissel t. Bioconjug Chem. 2012 Jan 18;23(1):3-20. doi: 10.1021/bc200296q. Epub 2011 Nov 1. Bioconjug Chem. 2012. PMID: 21999216 Review.

9

Amphiphilic biodegradable PEG-PCL-PEI triblock copolymers for FRET-capable in vitro and in vivo delivery of siRNA and quantum dots.

Endres T, Zheng M, Kılıç A, Turowska A, Beck-Broichsitter M, Renz H, Merkel OM, Kissel T. Endres T, et al. Among authors: kissel t. Mol Pharm. 2014 Apr 7;11(4):1273-81. doi: 10.1021/mp400744a. Epub 2014 Mar 12. Mol Pharm. 2014. PMID: 24592902

10

Efficient and Tumor Targeted siRNA Delivery by Polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate (PEI-PCL-PEG-Fol).

Liu L, Zheng M, Librizzi D, Renette T, Merkel OM, Kissel T. Liu L, et al. Among authors: kissel t. Mol Pharm. 2016 Jan 4;13(1):134-43. doi: 10.1021/acs.molpharmaceut.5b00575. Epub 2015 Dec 16. Mol Pharm. 2016. PMID: 26641134

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