Sproat B - Search Results

1

Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity.

Merkel OM, Mintzer MA, Librizzi D, Samsonova O, Dicke T, Sproat B, Garn H, Barth PJ, Simanek EE, Kissel T. Merkel OM, et al. Among authors: sproat b. Mol Pharm. 2010 Aug 2;7(4):969-83. doi: 10.1021/mp100101s. Mol Pharm. 2010. PMID: 20524664 Free PMC article.

2

Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance.

Merkel OM, Beyerle A, Librizzi D, Pfestroff A, Behr TM, Sproat B, Barth PJ, Kissel T. Merkel OM, et al. Among authors: sproat b. Mol Pharm. 2009 Jul-Aug;6(4):1246-60. doi: 10.1021/mp900107v. Mol Pharm. 2009. PMID: 19606864

3

Biophysical characterization of hyper-branched polyethylenimine-graft-polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery.

Liu Y, Samsonova O, Sproat B, Merkel O, Kissel T. Liu Y, et al. Among authors: sproat b. J Control Release. 2011 Aug 10;153(3):262-8. doi: 10.1016/j.jconrel.2011.04.017. Epub 2011 Apr 23. J Control Release. 2011. PMID: 21549166

4

Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression.

Jensen LB, Griger J, Naeye B, Varkouhi AK, Raemdonck K, Schiffelers R, Lammers T, Storm G, de Smedt SC, Sproat BS, Nielsen HM, Foged C. Jensen LB, et al. Among authors: sproat bs. Pharm Res. 2012 Mar;29(3):669-82. doi: 10.1007/s11095-011-0589-0. Epub 2011 Oct 5. Pharm Res. 2012. PMID: 21971827

5

PEGylation of biodegradable dextran nanogels for siRNA delivery.

Naeye B, Raemdonck K, Remaut K, Sproat B, Demeester J, De Smedt SC. Naeye B, et al. Among authors: sproat b. Eur J Pharm Sci. 2010 Jul 11;40(4):342-51. doi: 10.1016/j.ejps.2010.04.010. Epub 2010 May 7. Eur J Pharm Sci. 2010. PMID: 20435139 Free article.

6

Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.

Moschos SA, Jones SW, Perry MM, Williams AE, Erjefalt JS, Turner JJ, Barnes PJ, Sproat BS, Gait MJ, Lindsay MA. Moschos SA, et al. Bioconjug Chem. 2007 Sep-Oct;18(5):1450-9. doi: 10.1021/bc070077d. Epub 2007 Aug 21. Bioconjug Chem. 2007. PMID: 17711319 Free PMC article.

7

Chemical nucleic acid synthesis, modification and labelling.

Sproat BS. Sproat BS. Curr Opin Biotechnol. 1993 Feb;4(1):20-8. doi: 10.1016/0958-1669(93)90027-t. Curr Opin Biotechnol. 1993. PMID: 7763388 Review.

8

Studying pre-mRNA splicing using antisense 2-OMe RNA oligonucleotides.

Lamond AI, Barabino S, Blencowe BJ, Sproat B, Ryder U. Lamond AI, et al. Among authors: sproat b. Mol Biol Rep. 1990;14(2-3):201. doi: 10.1007/BF00360473. Mol Biol Rep. 1990. PMID: 1694562 No abstract available.

9

Chemical synthesis of a gene for somatomedin C.

Sproat BS, Gait MJ. Sproat BS, et al. Nucleic Acids Res. 1985 Apr 25;13(8):2959-77. doi: 10.1093/nar/13.8.2959. Nucleic Acids Res. 1985. PMID: 2987870 Free PMC article.

10

Synthesis of 2'-O-alkyloligoribonucleotides.

Sproat BS. Sproat BS. Methods Mol Biol. 1993;20:115-41. doi: 10.1385/0-89603-281-7:115. Methods Mol Biol. 1993. PMID: 8242133 No abstract available.

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