de Jonge H - Search Results

1

Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients.

Kuypers DR, Naesens M, de Jonge H, Lerut E, Verbeke K, Vanrenterghem Y. Kuypers DR, et al. Among authors: de jonge h. Ther Drug Monit. 2010 Aug;32(4):394-404. doi: 10.1097/FTD.0b013e3181e06818. Ther Drug Monit. 2010. PMID: 20526235

2

CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients.

Kuypers DR, de Jonge H, Naesens M, Lerut E, Verbeke K, Vanrenterghem Y. Kuypers DR, et al. Among authors: de jonge h. Clin Pharmacol Ther. 2007 Dec;82(6):711-25. doi: 10.1038/sj.clpt.6100216. Epub 2007 May 9. Clin Pharmacol Ther. 2007. PMID: 17495880

3

In vivo CYP3A activity is significantly lower in cyclosporine-treated as compared with tacrolimus-treated renal allograft recipients.

de Jonge H, de Loor H, Verbeke K, Vanrenterghem Y, Kuypers DR. de Jonge H, et al. Among authors: de loor h. Clin Pharmacol Ther. 2011 Sep;90(3):414-22. doi: 10.1038/clpt.2011.130. Epub 2011 Jul 13. Clin Pharmacol Ther. 2011. PMID: 21753749

4

In vivo CYP3A4 activity, CYP3A5 genotype, and hematocrit predict tacrolimus dose requirements and clearance in renal transplant patients.

de Jonge H, de Loor H, Verbeke K, Vanrenterghem Y, Kuypers DR. de Jonge H, et al. Among authors: de loor h. Clin Pharmacol Ther. 2012 Sep;92(3):366-75. doi: 10.1038/clpt.2012.109. Epub 2012 Aug 8. Clin Pharmacol Ther. 2012. PMID: 22871995

5

The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients.

de Jonge H, Elens L, de Loor H, van Schaik RH, Kuypers DR. de Jonge H, et al. Among authors: de loor h. Pharmacogenomics J. 2015 Apr;15(2):144-52. doi: 10.1038/tpj.2014.49. Epub 2014 Oct 7. Pharmacogenomics J. 2015. PMID: 25287072

6

Current target ranges of mycophenolic acid exposure and drug-related adverse events: a 5-year, open-label, prospective, clinical follow-up study in renal allograft recipients.

Kuypers DR, de Jonge H, Naesens M, de Loor H, Halewijck E, Dekens M, Vanrenterghem Y. Kuypers DR, et al. Among authors: de jonge h, de loor h. Clin Ther. 2008 Apr;30(4):673-83. doi: 10.1016/j.clinthera.2008.04.014. Clin Ther. 2008. PMID: 18498916 Clinical Trial.

7

Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients.

Kuypers DR, de Jonge H, Naesens M, Vanrenterghem Y. Kuypers DR, et al. Among authors: de jonge h. Pharmacogenet Genomics. 2008 Oct;18(10):861-8. doi: 10.1097/FPC.0b013e328307c26e. Pharmacogenet Genomics. 2008. PMID: 18704002

8

New insights into the pharmacokinetics and pharmacodynamics of the calcineurin inhibitors and mycophenolic acid: possible consequences for therapeutic drug monitoring in solid organ transplantation.

de Jonge H, Naesens M, Kuypers DR. de Jonge H, et al. Ther Drug Monit. 2009 Aug;31(4):416-35. doi: 10.1097/FTD.0b013e3181aa36cd. Ther Drug Monit. 2009. PMID: 19536049 Review.

9

Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts.

Naesens M, Lerut E, de Jonge H, Van Damme B, Vanrenterghem Y, Kuypers DR. Naesens M, et al. Among authors: de jonge h. J Am Soc Nephrol. 2009 Nov;20(11):2468-80. doi: 10.1681/ASN.2009020192. Epub 2009 Sep 17. J Am Soc Nephrol. 2009. PMID: 19762492 Free PMC article.

10

Reduced C0 concentrations and increased dose requirements in renal allograft recipients converted to the novel once-daily tacrolimus formulation.

de Jonge H, Kuypers DR, Verbeke K, Vanrenterghem Y. de Jonge H, et al. Transplantation. 2010 Sep 15;90(5):523-9. doi: 10.1097/TP.0b013e3181e9feda. Transplantation. 2010. PMID: 20592652

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