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Page 1
6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.
Micheli F, Cavanni P, Andreotti D, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Carletti R, Checchia A, Corsi M, Fazzolari E, Fontana S, Marchioro C, Merlo-Pich E, Negri M, Oliosi B, Ratti E, Read KD, Roscic M, Sartori I, Spada S, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L, Di Fabio R. Micheli F, et al. Among authors: arban r. J Med Chem. 2010 Jul 8;53(13):4989-5001. doi: 10.1021/jm100481d. J Med Chem. 2010. PMID: 20527970
Dihydropyrrole[2,3-d]pyridine derivatives as novel corticotropin-releasing factor-1 antagonists: mapping of the receptor binding pocket by in silico docking studies.
Di Fabio R, Arban R, Bernasconi G, Braggio S, Blaney FE, Capelli AM, Castiglioni E, Donati D, Fazzolari E, Ratti E, Feriani A, Contini S, Gentile G, Ghirlanda D, Sabbatini FM, Andreotti D, Spada S, Marchioro C, Worby A, St-Denis Y. Di Fabio R, et al. Among authors: arban r. J Med Chem. 2008 Nov 27;51(22):7273-86. doi: 10.1021/jm800743q. J Med Chem. 2008. PMID: 18975927
Synthesis and pharmacological characterization of novel druglike corticotropin-releasing factor 1 antagonists.
Di Fabio R, St-Denis Y, Sabbatini FM, Andreotti D, Arban R, Bernasconi G, Braggio S, Blaney FE, Capelli AM, Castiglioni E, Di Modugno E, Donati D, Fazzolari E, Ratti E, Feriani A, Contini S, Gentile G, Ghirlanda D, Provera S, Marchioro C, Roberts KL, Mingardi A, Mattioli M, Nalin A, Pavone F, Spada S, Trist DG, Worby A. Di Fabio R, et al. Among authors: arban r. J Med Chem. 2008 Dec 11;51(23):7370-9. doi: 10.1021/jm800744m. J Med Chem. 2008. PMID: 18989952
1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: a new series of potent and selective triple reuptake inhibitors.
Micheli F, Cavanni P, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Checchia A, Davalli S, Di Fabio R, Fazzolari E, Fontana S, Marchioro C, Minick D, Negri M, Oliosi B, Read KD, Sartori I, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L. Micheli F, et al. Among authors: arban r. J Med Chem. 2010 Mar 25;53(6):2534-51. doi: 10.1021/jm901818u. J Med Chem. 2010. PMID: 20170186
Design and synthesis of novel tricyclic benzoxazines as potent 5-HT(1A/B/D) receptor antagonists leading to the discovery of 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide (GSK588045).
Bromidge SM, Arban R, Bertani B, Bison S, Borriello M, Cavanni P, Dal Forno G, Di-Fabio R, Donati D, Fontana S, Gianotti M, Gordon LJ, Granci E, Leslie CP, Moccia L, Pasquarello A, Sartori I, Sava A, Watson JM, Worby A, Zonzini L, Zucchelli V. Bromidge SM, et al. Among authors: arban r. J Med Chem. 2010 Aug 12;53(15):5827-43. doi: 10.1021/jm100482n. J Med Chem. 2010. PMID: 20590088
Substituted tetraazaacenaphthylenes as potent CRF1 receptor antagonists for the treatment of depression and anxiety.
St-Denis Y, Di Fabio R, Bernasconi G, Castiglioni E, Contini S, Donati D, Fazzolari E, Gentile G, Ghirlanda D, Marchionni C, Messina F, Micheli F, Pavone F, Pasquarello A, Sabbatini FM, Zampori MG, Arban R, Vitulli G. St-Denis Y, et al. Among authors: arban r. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3713-6. doi: 10.1016/j.bmcl.2005.05.040. Bioorg Med Chem Lett. 2005. PMID: 15946843
Enantiomerically pure tetrahydroquinoline derivatives as in vivo potent antagonists of the glycine binding site associated to the NMDA receptor.
Di Fabio R, Tranquillini E, Bertani B, Alvaro G, Micheli F, Sabbatini F, Pizzi MD, Pentassuglia G, Pasquarello A, Messeri T, Donati D, Ratti E, Arban R, Dal Forno G, Reggiani A, Barnaby RJ. Di Fabio R, et al. Among authors: arban r. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3863-6. doi: 10.1016/j.bmcl.2003.06.001. Bioorg Med Chem Lett. 2003. PMID: 14552796
Cyclopenta[d]pyrimidines and dihydropyrrolo[2,3-d]pyrimidines as potent and selective corticotropin-releasing factor 1 receptor antagonists.
Arban R, Benedetti R, Bonanomi G, Capelli AM, Castiglioni E, Contini S, Degiorgis F, Di Felice P, Donati D, Fazzolari E, Gentile G, Marchionni C, Marchioro C, Messina F, Micheli F, Oliosi B, Pavone F, Pasquarello A, Perini B, Rinaldi M, Sabbatini FM, Vitulli G, Zarantonello P, Di Fabio R, St-Denis Y. Arban R, et al. ChemMedChem. 2007 Apr;2(4):528-40. doi: 10.1002/cmdc.200600257. ChemMedChem. 2007. PMID: 17335099
5-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-2(1H)-quinolinones and 3,4-dihydro-2(1H)-quinolinones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors. Part 3.
Bromidge SM, Arban R, Bertani B, Borriello M, Capelli AM, Di-Fabio R, Faedo S, Gianotti M, Gordon LJ, Granci E, Pasquarello A, Spada SK, Worby A, Zonzini L, Zucchelli V. Bromidge SM, et al. Among authors: arban r. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7092-6. doi: 10.1016/j.bmcl.2010.09.085. Epub 2010 Sep 27. Bioorg Med Chem Lett. 2010. PMID: 20951584
63 results