Chen CS - Search Results

1

The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo.

Lucas DM, Alinari L, West DA, Davis ME, Edwards RB, Johnson AJ, Blum KA, Hofmeister CC, Freitas MA, Parthun MR, Wang D, Lehman A, Zhang X, Jarjoura D, Kulp SK, Croce CM, Grever MR, Chen CS, Baiocchi RA, Byrd JC. Lucas DM, et al. Among authors: chen cs. PLoS One. 2010 Jun 3;5(6):e10941. doi: 10.1371/journal.pone.0010941. PLoS One. 2010. PMID: 20532179 Free PMC article.

2

Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancer.

Kulp SK, Chen CS, Wang DS, Chen CY, Chen CS. Kulp SK, et al. Among authors: chen cs, chen cy. Clin Cancer Res. 2006 Sep 1;12(17):5199-206. doi: 10.1158/1078-0432.CCR-06-0429. Clin Cancer Res. 2006. Retraction in: Clin Cancer Res. 2019 May 1;25(9):2940. doi: 10.1158/1078-0432.CCR-19-0731. PMID: 16951239 Retracted.

3

A rationally designed histone deacetylase inhibitor with distinct antitumor activity against ovarian cancer.

Yang YT, Balch C, Kulp SK, Mand MR, Nephew KP, Chen CS. Yang YT, et al. Among authors: chen cs. Neoplasia. 2009 Jun;11(6):552-63, 3 p following 563. doi: 10.1593/neo.09204. Neoplasia. 2009. PMID: 19484144 Free PMC article.

4

AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit.

Lin TY, Fenger J, Murahari S, Bear MD, Kulp SK, Wang D, Chen CS, Kisseberth WC, London CA. Lin TY, et al. Among authors: chen cs. Blood. 2010 May 27;115(21):4217-25. doi: 10.1182/blood-2009-07-231985. Epub 2010 Mar 16. Blood. 2010. PMID: 20233974 Free PMC article.

5

FTY720 shows promising in vitro and in vivo preclinical activity by downmodulating Cyclin D1 and phospho-Akt in mantle cell lymphoma.

Liu Q, Alinari L, Chen CS, Yan F, Dalton JT, Lapalombella R, Zhang X, Mani R, Lin T, Byrd JC, Baiocchi RA, Muthusamy N. Liu Q, et al. Among authors: chen cs. Clin Cancer Res. 2010 Jun 15;16(12):3182-92. doi: 10.1158/1078-0432.CCR-09-2484. Epub 2010 May 11. Clin Cancer Res. 2010. PMID: 20460491 Free PMC article.

6

Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42.

Henderson SE, Ding LY, Mo X, Bekaii-Saab T, Kulp SK, Chen CS, Huang PH. Henderson SE, et al. Among authors: chen cs. Neoplasia. 2016 Dec;18(12):765-774. doi: 10.1016/j.neo.2016.10.003. Epub 2016 Nov 25. Neoplasia. 2016. PMID: 27889645 Free PMC article.

7

Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors.

Lu Q, Yang YT, Chen CS, Davis M, Byrd JC, Etherton MR, Umar A, Chen CS. Lu Q, et al. Among authors: chen cs. J Med Chem. 2004 Jan 15;47(2):467-74. doi: 10.1021/jm0303655. J Med Chem. 2004. PMID: 14711316

8

A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2-independent mechanism.

Johnson AJ, Smith LL, Zhu J, Heerema NA, Jefferson S, Mone A, Grever M, Chen CS, Byrd JC. Johnson AJ, et al. Among authors: chen cs. Blood. 2005 Mar 15;105(6):2504-9. doi: 10.1182/blood-2004-05-1957. Epub 2004 Sep 28. Blood. 2005. PMID: 15454489 Free article.

9

Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder.

Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Blaser BW, Freud AG, Chou J, Chen CS, Xiao JJ, Parthun M, Chan KK, Eisenbeis CF, Ferketich AK, Grever MR, Chen CS, Caligiuri MA. Roychowdhury S, et al. Among authors: chen cs. J Natl Cancer Inst. 2004 Oct 6;96(19):1447-57. doi: 10.1093/jnci/djh271. J Natl Cancer Inst. 2004. PMID: 15467034

10

Efficacy of a novel histone deacetylase inhibitor in murine models of hepatocellular carcinoma.

Lu YS, Kashida Y, Kulp SK, Wang YC, Wang D, Hung JH, Tang M, Lin ZZ, Chen TJ, Cheng AL, Chen CS. Lu YS, et al. Among authors: chen cs, chen tj. Hepatology. 2007 Oct;46(4):1119-30. doi: 10.1002/hep.21804. Hepatology. 2007. PMID: 17654699

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