Zhang X - Search Results

1

Lead detoxification activity and ADMET hepatotoxicity of N-(alpha-L-arabino-furanos-1-yl)-L-cysteine.

Zhao M, Wang Y, Huo C, Liu J, Li C, Zhang X, Peng L, Peng S. Zhao M, et al. Among authors: zhang x. Chem Res Toxicol. 2010 Jul 19;23(7):1282-5. doi: 10.1021/tx100155r. Chem Res Toxicol. 2010. PMID: 20540575

2

Methyl (11aS)-1,2,3,5,11,11a-hexahydro-3,3-dimethyl-1-oxo-6H-imidazo-[3',4':1,2]pyridin[3,4-b]indol-2-substituted acetates: synthesis and three-dimensional quantitative structure-activity relationship investigation as a class of novel vasodilators.

Liu J, Zhao M, Cui G, Zhang X, Wang J, Peng S. Liu J, et al. Among authors: zhang x. J Med Chem. 2008 Aug 14;51(15):4715-23. doi: 10.1021/jm800249j. Epub 2008 Jul 11. J Med Chem. 2008. PMID: 18616237

3

(3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.

Zheng M, Zhang X, Zhao M, Chang HW, Wang W, Wang Y, Peng S. Zheng M, et al. Among authors: zhang x. Bioorg Med Chem. 2008 Nov 1;16(21):9574-87. doi: 10.1016/j.bmc.2008.09.019. Epub 2008 Sep 12. Bioorg Med Chem. 2008. PMID: 18835178

4

Synthesis, evaluation and 3D QSAR analysis of novel estradiol-RGD octapeptide conjugates with oral anti-osteoporosis activity.

Liu J, Zhang X, Zhao M, Peng S. Liu J, et al. Among authors: zhang x. Eur J Med Chem. 2009 Apr;44(4):1689-704. doi: 10.1016/j.ejmech.2008.09.036. Epub 2008 Oct 7. Eur J Med Chem. 2009. PMID: 19004530

5

3D QSAR of novel estrogen-RGD peptide conjugates: getting insight into structural dependence of anti-osteoporosis activity and side effect of estrogen in ERT.

Zhao M, Liu J, Zhang X, Peng L, Li C, Peng S. Zhao M, et al. Among authors: zhang x. Bioorg Med Chem. 2009 May 15;17(10):3680-9. doi: 10.1016/j.bmc.2009.03.057. Epub 2009 Apr 5. Bioorg Med Chem. 2009. PMID: 19386502

6

Synthesis, DNA intercalation and 3D QSAR analysis of cis-2,4,5-trisubstituted-1,3-dithiolanes as a novel class of antitumor agents.

Huang F, Zhao M, Zhang X, Wang C, Qian K, Kuo RY, Morris-Natschke S, Lee KH, Peng S. Huang F, et al. Among authors: zhang x. Bioorg Med Chem. 2009 Aug 15;17(16):6085-95. doi: 10.1016/j.bmc.2009.06.011. Epub 2009 Jun 13. Bioorg Med Chem. 2009. PMID: 19631550

7

N-[2-chloro-9H-purin-6-yl]-N-cyclopropylglycylamino acids and derivatives: synthesis, evaluation as a class of novel analgesics, and 3D QSAR analysis.

Zhao J, Kang G, Wang W, Zhao M, Zhang X, Lu C, Mao W, Chang HW, Ye W, Peng S. Zhao J, et al. Among authors: zhang x. Bioorg Med Chem. 2009 Sep 1;17(17):6305-10. doi: 10.1016/j.bmc.2009.07.035. Epub 2009 Jul 23. Bioorg Med Chem. 2009. PMID: 19679482

8

A class of novel N-(3S-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-amino acid derivatives: their synthesis, anti-thrombotic activity evaluation, and 3D QSAR analysis.

Cheng S, Zhang X, Wang W, Zhao M, Zheng M, Chang HW, Wu J, Peng S. Cheng S, et al. Among authors: zhang x. Eur J Med Chem. 2009 Dec;44(12):4904-19. doi: 10.1016/j.ejmech.2009.08.002. Epub 2009 Aug 6. Eur J Med Chem. 2009. PMID: 19729231

9

2,3-Diamino acid modifying 3S-tetrahydroisoquinoline-3-carboxylic acids: leading to a class of novel agents with highly unfolded conformation, selective in vitro anti-platelet aggregation and potent in vivo anti-thrombotic activity.

Zhang X, Wang W, Cheng S, Zhao M, Zheng M, Chang HW, Wu J, Peng S. Zhang X, et al. Bioorg Med Chem. 2010 Feb 15;18(4):1536-54. doi: 10.1016/j.bmc.2010.01.009. Epub 2010 Jan 13. Bioorg Med Chem. 2010. PMID: 20122838

10

Benzyl 1,2,3,5,11,11a-hexahydro-3,3-dimethyl-1-oxo-6H-imidazo[3',4':1,2]pyridin[3,4-b]indole-2-substituted acetates: One-pot-preparation, anti-tumor activity, docking toward DNA and 3D QSAR analysis.

Liu J, Zhao M, Qian K, Zhang X, Lee KH, Wu J, Liu YN, Peng S. Liu J, et al. Among authors: zhang x. Bioorg Med Chem. 2010 Mar 1;18(5):1910-7. doi: 10.1016/j.bmc.2010.01.038. Epub 2010 Jan 25. Bioorg Med Chem. 2010. PMID: 20171109

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