Role of the helical structure of the N-terminal region of Plasmodium falciparum merozoite surface protein 2 in fibril formation and membrane interaction.
Zhang X, Adda CG, Low A, Zhang J, Zhang W, Sun H, Tu X, Anders RF, Norton RS.
Zhang X, et al. Among authors: low a.
Biochemistry. 2012 Feb 21;51(7):1380-7. doi: 10.1021/bi201880s. Epub 2012 Feb 8.
Biochemistry. 2012.
PMID: 22304430
Merozoite surface protein 2 (MSP2), an abundant glycosylphosphatidylinositol-anchored protein on the surface of Plasmodium falciparum merozoites, is a promising malaria vaccine candidate. MSP2 is intrinsically disordered and forms amyloid-like fibrils in solution under phy …
Merozoite surface protein 2 (MSP2), an abundant glycosylphosphatidylinositol-anchored protein on the surface of Plasmodium falciparum merozo …