Kobayashi S - Search Results

1

The effects of diltiazem on hepatic drug metabolizing enzymes in man using antipyrine, trimethadione and debrisoquine as model substrates.

Sakai H, Kobayashi S, Hamada K, Iida S, Akita H, Tanaka E, Uchida E, Yasuhara H. Sakai H, et al. Among authors: kobayashi s. Br J Clin Pharmacol. 1991 Mar;31(3):353-5. doi: 10.1111/j.1365-2125.1991.tb05543.x. Br J Clin Pharmacol. 1991. PMID: 2054276 Free PMC article.

2

Pharmacokinetic study of trimethadione and its metabolite in blood, liver and brain by microdialysis in conscious, unrestrained rats.

Kurata N, Inagaki M, Iwase M, Nishimura Y, Kiuchi Y, Yamazaki Y, Kobayashi S, Oguchi K, Uchida E, Yasuhara H. Kurata N, et al. Among authors: kobayashi s. Res Commun Mol Pathol Pharmacol. 1995 Jul;89(1):45-56. Res Commun Mol Pathol Pharmacol. 1995. PMID: 7582861

3

The effects of inhibitors and substrates of different types of cytochrome P450 isozymes on serum dimethadione/trimethadione ratio in rats in vivo.

Nishimura Y, Kurata N, Kobayashi S, Uchida E, Yasuhara H. Nishimura Y, et al. Among authors: kobayashi s. Res Commun Mol Pathol Pharmacol. 1995 Feb;87(2):145-54. Res Commun Mol Pathol Pharmacol. 1995. PMID: 7749652

4

Trimethadione metabolism as a probe drug to estimate hepatic oxidizing capacity in rats.

Tanaka E, Ishikawa A, Kobayashi S, Yasuhara H, Misawa S, Kuroiwa Y. Tanaka E, et al. Among authors: kobayashi s. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Feb;104(2):205-7. doi: 10.1016/0742-8413(93)90025-g. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993. PMID: 8098675 Review.

5

The effects of malotilate on hepatic drug metabolizing systems in different strains of rats.

Kai K, Kobayashi S, Uchida E, Sakai H, Tanaka E, Kurata N, Yasuhara H. Kai K, et al. Among authors: kobayashi s. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;90(1):13-9. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988. PMID: 2904852

6

Strain differences of antipyrine, trimethadione, and debrisoquine metabolism in female rats.

Tanaka E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Among authors: kobayashi s. Res Commun Chem Pathol Pharmacol. 1990 Aug;69(2):233-6. Res Commun Chem Pathol Pharmacol. 1990. PMID: 2396050 No abstract available.

7

Antipyrine metabolism in female Lewis and Dark Agouti strains of rats, which are extensive and poor metabolizers of debrisoquine, respectively.

Tanaka E, Kobayashi S, Uchida E, Oguchi K, Yasuhara H. Tanaka E, et al. Among authors: kobayashi s. Jpn J Pharmacol. 1989 Mar;49(3):433-5. doi: 10.1254/jjp.49.433. Jpn J Pharmacol. 1989. PMID: 2747044 Free article.

8

A method for estimation of hepatic drug-metabolizing capacity: determination of concentration of trimethadione and its metabolite in human serum.

Kobayashi S, Tanaka E, Oguchi K, Yoshida T, Kuroiwa Y, Yasuhara H. Kobayashi S, et al. J Pharmacobiodyn. 1984 May;7(5):329-35. doi: 10.1248/bpb1978.7.329. J Pharmacobiodyn. 1984. PMID: 6470930

9

Antipyrine concentrations in liver and blood monitored by microdialysis of unrestrained conscious rats.

Kurata N, Inagaki M, Kobayashi S, Nishimura Y, Oguchi K, Yasuhara H. Kurata N, et al. Among authors: kobayashi s. Res Commun Chem Pathol Pharmacol. 1993 Mar;79(3):363-9. Res Commun Chem Pathol Pharmacol. 1993. PMID: 8480081

10

Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans.

Tanaka E, Ishikawa A, Abei M, Kobayashi S. Tanaka E, et al. Among authors: kobayashi s. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Nov;115(3):211-6. doi: 10.1016/s0742-8413(96)00102-8. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996. PMID: 9375358 Review.

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