Chandrashekaran IR - Search Results

1

Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2.

Chandrashekaran IR, Adda CG, MacRaild CA, Anders RF, Norton RS. Chandrashekaran IR, et al. Biochemistry. 2010 Jul 20;49(28):5899-908. doi: 10.1021/bi902197x. Biochemistry. 2010. PMID: 20545323

2

Inside-out: Antibody-binding reveals potential folding hinge-points within the SARS-CoV-2 replication co-factor nsp9.

Pan Y, Chandrashekaran IR, Tennant L, Rossjohn J, Littler DR. Pan Y, et al. Among authors: chandrashekaran ir. PLoS One. 2023 Apr 10;18(4):e0283194. doi: 10.1371/journal.pone.0283194. eCollection 2023. PLoS One. 2023. PMID: 37036856 Free PMC article.

3

Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.

Whitehouse RL, Alwan WS, Ilyichova OV, Taylor AJ, Chandrashekaran IR, Mohanty B, Doak BC, Scanlon MJ. Whitehouse RL, et al. Among authors: chandrashekaran ir. RSC Med Chem. 2022 Nov 29;14(1):135-143. doi: 10.1039/d2md00253a. eCollection 2023 Jan 25. RSC Med Chem. 2022. PMID: 36760747 Free PMC article.

4

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs.

Chandrashekaran IR, Yao S, Wang CC, Bansal PS, Alewood PF, Forbes BE, Wallace JC, Bach LA, Norton RS. Chandrashekaran IR, et al. Biochemistry. 2007 Mar 20;46(11):3065-74. doi: 10.1021/bi0619876. Epub 2007 Feb 17. Biochemistry. 2007. PMID: 17305365

5

Merozoite surface protein 2 of Plasmodium falciparum: expression, structure, dynamics, and fibril formation of the conserved N-terminal domain.

Low A, Chandrashekaran IR, Adda CG, Yao S, Sabo JK, Zhang X, Soetopo A, Anders RF, Norton RS. Low A, et al. Among authors: chandrashekaran ir. Biopolymers. 2007 Sep;87(1):12-22. doi: 10.1002/bip.20764. Biopolymers. 2007. PMID: 17516503

6

EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2.

Chandrashekaran IR, Adda CG, Macraild CA, Anders RF, Norton RS. Chandrashekaran IR, et al. Arch Biochem Biophys. 2011 Sep 15;513(2):153-7. doi: 10.1016/j.abb.2011.07.008. Epub 2011 Jul 19. Arch Biochem Biophys. 2011. PMID: 21784057 Free PMC article.

7

The N-terminal domains of SOCS proteins: a conserved region in the disordered N-termini of SOCS4 and 5.

Feng ZP, Chandrashekaran IR, Low A, Speed TP, Nicholson SE, Norton RS. Feng ZP, et al. Among authors: chandrashekaran ir. Proteins. 2012 Mar;80(3):946-57. doi: 10.1002/prot.23252. Proteins. 2012. PMID: 22423360

8

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.

Linossi EM, Chandrashekaran IR, Kolesnik TB, Murphy JM, Webb AI, Willson TA, Kedzierski L, Bullock AN, Babon JJ, Norton RS, Nicola NA, Nicholson SE. Linossi EM, et al. Among authors: chandrashekaran ir. PLoS One. 2013 Aug 21;8(8):e70536. doi: 10.1371/journal.pone.0070536. eCollection 2013. PLoS One. 2013. PMID: 23990909 Free PMC article.

9

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO.

Lim SS, Yang W, Krishnarjuna B, Kannan Sivaraman K, Chandrashekaran IR, Kass I, MacRaild CA, Devine SM, Debono CO, Anders RF, Scanlon MJ, Scammells PJ, Norton RS, McGowan S. Lim SS, et al. Among authors: chandrashekaran ir. Biochemistry. 2014 Nov 25;53(46):7310-20. doi: 10.1021/bi5012089. Epub 2014 Nov 14. Biochemistry. 2014. PMID: 25360546

10

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold.

Devine SM, Mulcair MD, Debono CO, Leung EW, Nissink JW, Lim SS, Chandrashekaran IR, Vazirani M, Mohanty B, Simpson JS, Baell JB, Scammells PJ, Norton RS, Scanlon MJ. Devine SM, et al. Among authors: chandrashekaran ir. J Med Chem. 2015 Feb 12;58(3):1205-14. doi: 10.1021/jm501402x. Epub 2015 Jan 16. J Med Chem. 2015. PMID: 25559643

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