Hochalter JB - Search Results

1

Preferential glutathione conjugation of a reverse diol epoxide compared with a bay region diol epoxide of benzo[a]pyrene in human hepatocytes.

Upadhyaya P, Hochalter JB, Balbo S, McIntee EJ, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Drug Metab Dispos. 2010 Sep;38(9):1397-402. doi: 10.1124/dmd.110.034181. Epub 2010 Jun 14. Drug Metab Dispos. 2010. PMID: 20547966 Free PMC article.

2

Quantitation of enantiomers of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]-pyrene in human urine: evidence supporting metabolic activation of benzo[a]pyrene via the bay region diol epoxide.

Hecht SS, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Mutagenesis. 2014 Sep;29(5):351-6. doi: 10.1093/mutage/geu024. Epub 2014 Jul 21. Mutagenesis. 2014. PMID: 25053834 Free PMC article.

3

Quantitation of N-acetyl-S-(9,10-dihydro-9-hydroxy-10-phenanthryl)-L-cysteine in human urine: comparison with glutathione-S-transferase genotypes in smokers.

Upadhyaya P, Rao P, Hochalter JB, Li ZZ, Villalta PW, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Chem Res Toxicol. 2006 Sep;19(9):1234-40. doi: 10.1021/tx060096w. Chem Res Toxicol. 2006. PMID: 16978029 Free PMC article.

4

Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms.

Hecht SS, Villalta PW, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Carcinogenesis. 2008 May;29(5):937-43. doi: 10.1093/carcin/bgn015. Epub 2008 May 13. Carcinogenesis. 2008. PMID: 18477646 Free PMC article.

5

Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Chem Res Toxicol. 2008 Jul;21(7):1468-76. doi: 10.1021/tx8001109. Epub 2008 Jun 21. Chem Res Toxicol. 2008. PMID: 18570389 Free PMC article.

6

Preferential glutathione conjugation of a reverse diol epoxide compared to a bay region diol epoxide of phenanthrene in human hepatocytes: relevance to molecular epidemiology studies of glutathione-s-transferase polymorphisms and cancer.

Hecht SS, Berg JZ, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2009 Mar 16;22(3):426-32. doi: 10.1021/tx800315m. Chem Res Toxicol. 2009. PMID: 19187038 Free PMC article.

7

Analysis of phenanthrene and benzo[a]pyrene tetraol enantiomers in human urine: relevance to the bay region diol epoxide hypothesis of benzo[a]pyrene carcinogenesis and to biomarker studies.

Hecht SS, Carmella SG, Villalta PW, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2010 May 17;23(5):900-8. doi: 10.1021/tx9004538. Chem Res Toxicol. 2010. PMID: 20369855 Free PMC article.

8

Immediate consequences of cigarette smoking: rapid formation of polycyclic aromatic hydrocarbon diol epoxides.

Zhong Y, Carmella SG, Upadhyaya P, Hochalter JB, Rauch D, Oliver A, Jensen J, Hatsukami D, Wang J, Zimmerman C, Hecht SS. Zhong Y, et al. Among authors: hochalter jb. Chem Res Toxicol. 2011 Feb 18;24(2):246-52. doi: 10.1021/tx100345x. Epub 2010 Dec 27. Chem Res Toxicol. 2011. PMID: 21184614 Free PMC article.

9

Quantitation of a minor enantiomer of phenanthrene tetraol in human urine: correlations with levels of overall phenanthrene tetraol, benzo[a]pyrene tetraol, and 1-hydroxypyrene.

Hochalter JB, Zhong Y, Han S, Carmella SG, Hecht SS. Hochalter JB, et al. Chem Res Toxicol. 2011 Feb 18;24(2):262-8. doi: 10.1021/tx100391z. Epub 2011 Jan 13. Chem Res Toxicol. 2011. PMID: 21229973 Free PMC article.

10

Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung.

Villalta PW, Hochalter JB, Hecht SS. Villalta PW, et al. Among authors: hochalter jb. Anal Chem. 2017 Dec 5;89(23):12735-12742. doi: 10.1021/acs.analchem.7b02856. Epub 2017 Nov 17. Anal Chem. 2017. PMID: 29111668 Free PMC article.

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