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CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
Prakash C, Wang W, O'Connell T, Johnson KA. Prakash C, et al. Drug Metab Dispos. 2008 Oct;36(10):2093-103. doi: 10.1124/dmd.108.022897. Epub 2008 Jul 24. Drug Metab Dispos. 2008. PMID: 18653741
748 results