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Page 1
Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.
Arnt J, Bang-Andersen B, Grayson B, Bymaster FP, Cohen MP, DeLapp NW, Giethlen B, Kreilgaard M, McKinzie DL, Neill JC, Nelson DL, Nielsen SM, Poulsen MN, Schaus JM, Witten LM. Arnt J, et al. Int J Neuropsychopharmacol. 2010 Sep;13(8):1021-33. doi: 10.1017/S1461145710000659. Epub 2010 Jun 23. Int J Neuropsychopharmacol. 2010. PMID: 20569520 Free article.
Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsychotic potential.
Hertel P, Didriksen M, Pouzet B, Brennum LT, Søby KK, Larsen AK, Christoffersen CT, Ramirez T, Marcus MM, Svensson TH, Di Matteo V, Esposito E, Bang-Andersen B, Arnt J. Hertel P, et al. Eur J Pharmacol. 2007 Nov 14;573(1-3):148-60. doi: 10.1016/j.ejphar.2007.06.052. Epub 2007 Jul 4. Eur J Pharmacol. 2007. PMID: 17689529
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder.
Mørk A, Pehrson A, Brennum LT, Nielsen SM, Zhong H, Lassen AB, Miller S, Westrich L, Boyle NJ, Sánchez C, Fischer CW, Liebenberg N, Wegener G, Bundgaard C, Hogg S, Bang-Andersen B, Stensbøl TB. Mørk A, et al. J Pharmacol Exp Ther. 2012 Mar;340(3):666-75. doi: 10.1124/jpet.111.189068. Epub 2011 Dec 9. J Pharmacol Exp Ther. 2012. PMID: 22171087
Discovery and development of 11C-Lu AE92686 as a radioligand for PET imaging of phosphodiesterase10A in the brain.
Kehler J, Kilburn JP, Estrada S, Christensen SR, Wall A, Thibblin A, Lubberink M, Bundgaard C, Brennum LT, Steiniger-Brach B, Christoffersen CT, Timmermann S, Kreilgaard M, Antoni G, Bang-Andersen B, Nielsen J. Kehler J, et al. J Nucl Med. 2014 Sep;55(9):1513-8. doi: 10.2967/jnumed.114.140178. Epub 2014 Jul 3. J Nucl Med. 2014. PMID: 24994928 Free article.
Synthesis and SAR studies of analogues of 4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide (Lu AA41063) as adenosine A2A receptor ligands with improved aqueous solubility.
Mikkelsen GK, Langgård M, Schrøder TJ, Kreilgaard M, Jørgensen EB, Brandt G, Griffon Y, Boffey R, Bang-Andersen B. Mikkelsen GK, et al. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1212-6. doi: 10.1016/j.bmcl.2015.01.062. Epub 2015 Feb 7. Bioorg Med Chem Lett. 2015. PMID: 25701253
Neurokinin-3 Receptor Binding in Guinea Pig, Monkey, and Human Brain: In Vitro and in Vivo Imaging Using the Novel Radioligand, [18F]Lu AF10628.
Varnäs K, Finnema SJ, Stepanov V, Takano A, Tóth M, Svedberg M, Møller Nielsen S, Khanzhin NA, Juhl K, Bang-Andersen B, Halldin C, Farde L. Varnäs K, et al. Int J Neuropsychopharmacol. 2016 Aug 12;19(8):pyw023. doi: 10.1093/ijnp/pyw023. Print 2016 Aug. Int J Neuropsychopharmacol. 2016. PMID: 26993630 Free PMC article.
66 results