Besch R - Search Results

1

Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1.

Zall H, Weber A, Besch R, Zantl N, Häcker G. Zall H, et al. Among authors: besch r. Mol Cancer. 2010 Jun 24;9:164. doi: 10.1186/1476-4598-9-164. Mol Cancer. 2010. PMID: 20576107 Free PMC article.

2

Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells.

Weber A, Kirejczyk Z, Besch R, Potthoff S, Leverkus M, Häcker G. Weber A, et al. Among authors: besch r. Cell Death Differ. 2010 Jun;17(6):942-51. doi: 10.1038/cdd.2009.190. Epub 2009 Dec 18. Cell Death Differ. 2010. PMID: 20019748

3

In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.

Senft D, Weber A, Saathoff F, Berking C, Heppt MV, Kammerbauer C, Rothenfusser S, Kellner S, Kurgyis Z, Besch R, Häcker G. Senft D, et al. Among authors: besch r. Cell Death Dis. 2015 Nov 26;6(11):e1996. doi: 10.1038/cddis.2015.341. Cell Death Dis. 2015. PMID: 26610208 Free PMC article.

4

Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells.

Besch R, Poeck H, Hohenauer T, Senft D, Häcker G, Berking C, Hornung V, Endres S, Ruzicka T, Rothenfusser S, Hartmann G. Besch R, et al. J Clin Invest. 2009 Aug;119(8):2399-411. doi: 10.1172/JCI37155. Epub 2009 Jul 20. J Clin Invest. 2009. PMID: 19620789 Free PMC article.

5

5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.

Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tüting T, Hartmann G. Poeck H, et al. Among authors: besch r. Nat Med. 2008 Nov;14(11):1256-63. doi: 10.1038/nm.1887. Epub 2008 Nov 2. Nat Med. 2008. PMID: 18978796

6

Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1.

Senft D, Berking C, Graf SA, Kammerbauer C, Ruzicka T, Besch R. Senft D, et al. Among authors: besch r. PLoS One. 2012;7(1):e30821. doi: 10.1371/journal.pone.0030821. Epub 2012 Jan 24. PLoS One. 2012. PMID: 22292048 Free PMC article.

7

The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.

Hohenauer T, Berking C, Schmidt A, Haferkamp S, Senft D, Kammerbauer C, Fraschka S, Graf SA, Irmler M, Beckers J, Flaig M, Aigner A, Höbel S, Hoffmann F, Hermeking H, Rothenfusser S, Endres S, Ruzicka T, Besch R. Hohenauer T, et al. Among authors: besch r. EMBO Mol Med. 2013 Jun;5(6):919-34. doi: 10.1002/emmm.201201862. Epub 2013 May 13. EMBO Mol Med. 2013. PMID: 23666755 Free PMC article.

8

Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III.

Wenzel M, Wunderlich M, Besch R, Poeck H, Willms S, Schwantes A, Kremer M, Sutter G, Endres S, Schmidt A, Rothenfusser S. Wenzel M, et al. Among authors: besch r. J Immunol. 2012 Jan 1;188(1):394-403. doi: 10.4049/jimmunol.1100523. Epub 2011 Dec 2. J Immunol. 2012. PMID: 22140256

9

A Bifunctional Approach of Immunostimulation and uPAR Inhibition Shows Potent Antitumor Activity in Melanoma.

Matheis F, Heppt MV, Graf SA, Düwell P, Kammerbauer C, Aigner A, Besch R, Berking C. Matheis F, et al. Among authors: besch r. J Invest Dermatol. 2016 Dec;136(12):2475-2484. doi: 10.1016/j.jid.2016.07.026. Epub 2016 Aug 3. J Invest Dermatol. 2016. PMID: 27498344 Free article.

10

Differential expression of melanoma-associated growth factors in keratinocytes and fibroblasts by ultraviolet A and ultraviolet B radiation.

Brenner M, Degitz K, Besch R, Berking C. Brenner M, et al. Among authors: besch r. Br J Dermatol. 2005 Oct;153(4):733-9. doi: 10.1111/j.1365-2133.2005.06780.x. Br J Dermatol. 2005. PMID: 16181453

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