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Fragment-based drug discovery of potent and selective MKK3/6 inhibitors.
Adams M, Kobayashi T, Lawson JD, Saitoh M, Shimokawa K, Bigi SV, Hixon MS, Smith CR, Tatamiya T, Goto M, Russo J, Grimshaw CE, Swann S. Adams M, et al. Among authors: kobayashi t. Bioorg Med Chem Lett. 2016 Feb 1;26(3):1086-1089. doi: 10.1016/j.bmcl.2015.11.054. Epub 2015 Nov 17. Bioorg Med Chem Lett. 2016. PMID: 26704264
Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure.
Okawa T, Aramaki Y, Yamamoto M, Kobayashi T, Fukumoto S, Toyoda Y, Henta T, Hata A, Ikeda S, Kaneko M, Hoffman ID, Sang BC, Zou H, Kawamoto T. Okawa T, et al. Among authors: kobayashi t. J Med Chem. 2017 Aug 24;60(16):6942-6990. doi: 10.1021/acs.jmedchem.7b00443. Epub 2017 Aug 3. J Med Chem. 2017. PMID: 28699740
Racial, Socioeconomic, and Geographic Disparities in Preamputation Vascular Care for Patients With Chronic Limb-Threatening Ischemia.
Ramadan OI, Yang L, Shultz K, Genovese E, Damrauer SM, Wang GJ, Secemsky EA, Treat-Jacobson DJ, Womeodu RJ, Fakorede FA, Nathan AS, Eberly LA, Julien HM, Kobayashi TJ, Groeneveld PW, Giri J, Fanaroff AC. Ramadan OI, et al. Among authors: kobayashi tj. Circ Cardiovasc Qual Outcomes. 2025 Jan 3:e010931. doi: 10.1161/CIRCOUTCOMES.124.010931. Online ahead of print. Circ Cardiovasc Qual Outcomes. 2025. PMID: 39749477
A Rational Approach to the Treatment of Acute Pulmonary Embolism.
Faggioni M, Giri J, Glassmoyer L, Kobayashi T. Faggioni M, et al. Among authors: kobayashi t. Annu Rev Med. 2025 Jan 2. doi: 10.1146/annurev-med-050423-085457. Online ahead of print. Annu Rev Med. 2025. PMID: 39745937 Review.
Efficacy of imeglimin in patients with type 2 diabetes mellitus complicated by metabolic dysfunction-associated steatotic liver disease: A multicentre study.
Fukunaga K, Morishita A, Imachi H, Oura K, Sato S, Kobayashi T, Saheki T, Yoshimura T, Komori K, Nakahara M, Tadokoro T, Fujita K, Tani J, Kobara H, Murao K. Fukunaga K, et al. Among authors: kobayashi t. Diabetes Obes Metab. 2024 Dec 26. doi: 10.1111/dom.16157. Online ahead of print. Diabetes Obes Metab. 2024. PMID: 39726210
14,908 results
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