Elowe N - Search Results

1

An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase.

Orlicky S, Tang X, Neduva V, Elowe N, Brown ED, Sicheri F, Tyers M. Orlicky S, et al. Among authors: elowe n. Nat Biotechnol. 2010 Jul;28(7):733-7. doi: 10.1038/nbt.1646. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581844 Free PMC article.

2

Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.

Ejim LJ, Blanchard JE, Koteva KP, Sumerfield R, Elowe NH, Chechetto JD, Brown ED, Junop MS, Wright GD. Ejim LJ, et al. J Med Chem. 2007 Feb 22;50(4):755-64. doi: 10.1021/jm061132r. J Med Chem. 2007. PMID: 17300162

3

Experimental screening of dihydrofolate reductase yields a "test set" of 50,000 small molecules for a computational data-mining and docking competition.

Elowe NH, Blanchard JE, Cechetto JD, Brown ED. Elowe NH, et al. J Biomol Screen. 2005 Oct;10(7):653-7. doi: 10.1177/1087057105281173. Epub 2005 Sep 16. J Biomol Screen. 2005. PMID: 16170050

4

High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase.

Blanchard JE, Elowe NH, Huitema C, Fortin PD, Cechetto JD, Eltis LD, Brown ED. Blanchard JE, et al. Chem Biol. 2004 Oct;11(10):1445-53. doi: 10.1016/j.chembiol.2004.08.011. Chem Biol. 2004. PMID: 15489171 Free PMC article.

5

Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity.

Elowe NH, Nutiu R, Allali-Hassani A, Cechetto JD, Hughes DW, Li Y, Brown ED. Elowe NH, et al. Angew Chem Int Ed Engl. 2006 Aug 25;45(34):5648-52. doi: 10.1002/anie.200601695. Angew Chem Int Ed Engl. 2006. PMID: 16856187 No abstract available.

6

Cystathionine beta-lyase is important for virulence of Salmonella enterica serovar Typhimurium.

Ejim LJ, D'Costa VM, Elowe NH, Loredo-Osti JC, Malo D, Wright GD. Ejim LJ, et al. Infect Immun. 2004 Jun;72(6):3310-4. doi: 10.1128/IAI.72.6.3310-3314.2004. Infect Immun. 2004. PMID: 15155634 Free PMC article.

7

An in vitro screen of bacterial lipopolysaccharide biosynthetic enzymes identifies an inhibitor of ADP-heptose biosynthesis.

De Leon GP, Elowe NH, Koteva KP, Valvano MA, Wright GD. De Leon GP, et al. Chem Biol. 2006 Apr;13(4):437-41. doi: 10.1016/j.chembiol.2006.02.010. Chem Biol. 2006. PMID: 16632256

8

Functional annotation of putative aminoglycoside antibiotic modifying proteins in Mycobacterium tuberculosis H37Rv.

Draker KA, Boehr DD, Elowe NH, Noga TJ, Wright GD. Draker KA, et al. J Antibiot (Tokyo). 2003 Feb;56(2):135-42. doi: 10.7164/antibiotics.56.135. J Antibiot (Tokyo). 2003. PMID: 12715873 Free article.

9

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes.

Saavedra OM, Isakovic L, Llewellyn DB, Zhan L, Bernstein N, Claridge S, Raeppel F, Vaisburg A, Elowe N, Petschner AJ, Rahil J, Beaulieu N, MacLeod AR, Delorme D, Besterman JM, Wahhab A. Saavedra OM, et al. Among authors: elowe n. Bioorg Med Chem Lett. 2009 May 15;19(10):2747-51. doi: 10.1016/j.bmcl.2009.03.113. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19362833

10

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors.

Isakovic L, Saavedra OM, Llewellyn DB, Claridge S, Zhan L, Bernstein N, Vaisburg A, Elowe N, Petschner AJ, Rahil J, Beaulieu N, Gauthier F, MacLeod AR, Delorme D, Besterman JM, Wahhab A. Isakovic L, et al. Among authors: elowe n. Bioorg Med Chem Lett. 2009 May 15;19(10):2742-6. doi: 10.1016/j.bmcl.2009.03.132. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19364644

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

22 results

Search Page

Filters