Zhai Y - Search Results

1

A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses.

Zhai Y, Wada T, Zhang B, Khadem S, Ren S, Kuruba R, Li S, Xie W. Zhai Y, et al. Mol Pharmacol. 2010 Oct;78(4):666-74. doi: 10.1124/mol.110.064618. Epub 2010 Jun 30. Mol Pharmacol. 2010. PMID: 20592274 Free PMC article.

2

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.

Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W. Zhou J, et al. Among authors: zhai y. J Biol Chem. 2006 May 26;281(21):15013-20. doi: 10.1074/jbc.M511116200. Epub 2006 Mar 23. J Biol Chem. 2006. PMID: 16556603 Free PMC article.

3

Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis.

Zhai Y, Pai HV, Zhou J, Amico JA, Vollmer RR, Xie W. Zhai Y, et al. Mol Endocrinol. 2007 Jan;21(1):138-47. doi: 10.1210/me.2006-0291. Epub 2006 Sep 14. Mol Endocrinol. 2007. PMID: 16973756

4

Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.

Uppal H, Saini SP, Moschetta A, Mu Y, Zhou J, Gong H, Zhai Y, Ren S, Michalopoulos GK, Mangelsdorf DJ, Xie W. Uppal H, et al. Among authors: zhai y. Hepatology. 2007 Feb;45(2):422-32. doi: 10.1002/hep.21494. Hepatology. 2007. PMID: 17256725

5

Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor.

Gong H, Guo P, Zhai Y, Zhou J, Uppal H, Jarzynka MJ, Song WC, Cheng SY, Xie W. Gong H, et al. Among authors: zhai y. Mol Endocrinol. 2007 Aug;21(8):1781-90. doi: 10.1210/me.2007-0187. Epub 2007 May 29. Mol Endocrinol. 2007. PMID: 17536009

6

The antiapoptotic role of pregnane X receptor in human colon cancer cells.

Zhou J, Liu M, Zhai Y, Xie W. Zhou J, et al. Among authors: zhai y. Mol Endocrinol. 2008 Apr;22(4):868-80. doi: 10.1210/me.2007-0197. Epub 2007 Dec 20. Mol Endocrinol. 2008. PMID: 18096695 Free PMC article.

7

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.

Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W. Zhou J, et al. Among authors: zhai y. Gastroenterology. 2008 Feb;134(2):556-67. doi: 10.1053/j.gastro.2007.11.037. Epub 2007 Nov 28. Gastroenterology. 2008. PMID: 18242221

8

Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization.

Uppal H, Zhai Y, Gangopadhyay A, Khadem S, Ren S, Moser JA, Xie W. Uppal H, et al. Among authors: zhai y. Hepatology. 2008 Apr;47(4):1331-42. doi: 10.1002/hep.22175. Hepatology. 2008. PMID: 18318438

9

The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity.

Gao J, He J, Zhai Y, Wada T, Xie W. Gao J, et al. Among authors: zhai y. J Biol Chem. 2009 Sep 18;284(38):25984-92. doi: 10.1074/jbc.M109.016808. Epub 2009 Jul 17. J Biol Chem. 2009. PMID: 19617349 Free PMC article.

10

Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism.

Xiao L, Xie X, Zhai Y. Xiao L, et al. Among authors: zhai y. Adv Drug Deliv Rev. 2010 Oct 30;62(13):1316-21. doi: 10.1016/j.addr.2010.07.006. Epub 2010 Jul 24. Adv Drug Deliv Rev. 2010. PMID: 20659512 Review.

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