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RORc expressing immune cells negatively regulate tertiary lymphoid structure formation and support their pro-tumorigenic functions.
Cinnamon E, Stein I, Zino E, Rabinovich S, Shovman Y, Schlesinger Y, Salame TM, Reich-Zeliger S, Albrecht T, Roessler S, Schirmacher P, Lotem M, Ben-Neriah Y, Parnas O, Pikarsky E. Cinnamon E, et al. Among authors: roessler s. J Hepatol. 2024 Dec 20:S0168-8278(24)02769-7. doi: 10.1016/j.jhep.2024.12.015. Online ahead of print. J Hepatol. 2024. PMID: 39710149 Free article.
Small-RNA sequencing reveals potential serum biomarkers for gallbladder cancer: Results from a three-stage collaborative study of large European prospective cohorts.
Blandino A, Scherer D, Boekstegers F, Rounge TB, Langseth H, Roessler S, Hveem K, Brenner H, Pechlivanis S, Waldenberger M, Lorenzo Bermejo J. Blandino A, et al. Among authors: roessler s. Eur J Cancer. 2025 Jan;214:115138. doi: 10.1016/j.ejca.2024.115138. Epub 2024 Nov 20. Eur J Cancer. 2025. PMID: 39579640 Free article.
DNA methylation classifier to diagnose pancreatic ductal adenocarcinoma metastases from different anatomical sites.
Calina TG, Perez E, Grafenhorst E, Benhamida J, Schallenberg S, Popescu A, Koch I, Janik T, Chen B, Ihlow J, Roessler S, Goeppert B, Sinn B, Bahra M, Calin GA, Taube ET, Pelzer U, Neumann CCM, Horst D, Knutsen E, Capper D, Dragomir MP. Calina TG, et al. Among authors: roessler s. Clin Epigenetics. 2024 Nov 10;16(1):156. doi: 10.1186/s13148-024-01768-x. Clin Epigenetics. 2024. PMID: 39523345 Free PMC article.
Proteomic profiling reveals CEACAM6 function in driving gallbladder cancer aggressiveness through integrin receptor, PRKCD and AKT/ERK signaling.
Sugiyanto RN, Metzger C, Inal A, Truckenmueller F, Gür K, Eiteneuer E, Huth T, Fraas A, Heinze I, Kirkpatrick J, Sticht C, Albrecht T, Goeppert B, Poth T, Pusch S, Mehrabi A, Schirmacher P, Ji J, Ori A, Roessler S. Sugiyanto RN, et al. Among authors: roessler s. Cell Death Dis. 2024 Oct 28;15(10):780. doi: 10.1038/s41419-024-07171-x. Cell Death Dis. 2024. PMID: 39468006 Free PMC article.
Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma.
Xu K, Kessler A, Nichetti F, Hoffmeister-Wittmann P, Scherr AL, Nader L, Kelmendi E, Schmitt N, Schwab M, García-Beccaria M, Sobol B, Nieto OA, Isele H, Gärtner U, Vaquero-Siguero N, Volk J, Korell F, Mock A, Heide D, Ramadori P, Lenoir B, Albrecht T, Hüllein J, Jäger D, Fröhling S, Springfeld C, Jackstadt R, Heikenwälder M, Dill MT, Roessler S, Goeppert B, Köhler BC. Xu K, et al. Among authors: roessler s. Liver Int. 2024 Nov;44(11):2950-2963. doi: 10.1111/liv.16069. Epub 2024 Aug 20. Liver Int. 2024. PMID: 39164890 Free article.
The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects.
Dropmann A, Alex S, Schorn K, Tong C, Caccamo T, Godoy P, Ilkavets I, Liebe R, Gonzalez D, Hengstler JG, Piiper A, Quagliata L, Matter MS, Waidmann O, Finkelmeier F, Feng T, Weiss TS, Rahbari N, Birgin E, Rasbach E, Roessler S, Breuhahn K, Tóth M, Ebert MP, Dooley S, Hammad S, Meindl-Beinker NM. Dropmann A, et al. Among authors: roessler s. Biochem Biophys Res Commun. 2024 Nov 5;732:150409. doi: 10.1016/j.bbrc.2024.150409. Epub 2024 Jul 16. Biochem Biophys Res Commun. 2024. PMID: 39033550 Free article.
Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis.
Grimsrud MM, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, Braadland PR, Charbel A, Metzger C, Albrecht T, Steiert TA, Schlesner M, Manns MP, Vogel A, Yaqub S, Karlsen TH, Schirmacher P, Boberg KM, Franke A, Roessler S, Folseraas T. Grimsrud MM, et al. Among authors: roessler s. Hepatol Commun. 2024 Jul 5;8(7):e0461. doi: 10.1097/HC9.0000000000000461. eCollection 2024 Jul 1. Hepatol Commun. 2024. PMID: 38967597 Free PMC article.
122 results