Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1.
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Potin D, et al. Among authors: fouquet a.
J Med Chem. 2006 Nov 30;49(24):6946-9. doi: 10.1021/jm0610806.
J Med Chem. 2006.
PMID: 17125246