Gutknecht L - Search Results

1

Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life.

Kriegebaum C, Song NN, Gutknecht L, Huang Y, Schmitt A, Reif A, Ding YQ, Lesch KP. Kriegebaum C, et al. Among authors: gutknecht l. Neurochem Int. 2010 Nov;57(5):512-7. doi: 10.1016/j.neuint.2010.06.015. Epub 2010 Jul 3. Neurochem Int. 2010. PMID: 20599453

2

Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation.

Gutknecht L, Jacob C, Strobel A, Kriegebaum C, Müller J, Zeng Y, Markert C, Escher A, Wendland J, Reif A, Mössner R, Gross C, Brocke B, Lesch KP. Gutknecht L, et al. Int J Neuropsychopharmacol. 2007 Jun;10(3):309-20. doi: 10.1017/S1461145706007437. Epub 2006 Dec 19. Int J Neuropsychopharmacol. 2007. PMID: 17176492 Free article.

3

Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice.

Gutknecht L, Waider J, Kraft S, Kriegebaum C, Holtmann B, Reif A, Schmitt A, Lesch KP. Gutknecht L, et al. J Neural Transm (Vienna). 2008 Aug;115(8):1127-32. doi: 10.1007/s00702-008-0096-6. Epub 2008 Jul 30. J Neural Transm (Vienna). 2008. PMID: 18665319

4

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.

Gutknecht L, Kriegebaum C, Waider J, Schmitt A, Lesch KP. Gutknecht L, et al. Eur Neuropsychopharmacol. 2009 Apr;19(4):266-82. doi: 10.1016/j.euroneuro.2008.12.005. Epub 2009 Feb 1. Eur Neuropsychopharmacol. 2009. PMID: 19181488

5

Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.

Gutknecht L, Araragi N, Merker S, Waider J, Sommerlandt FM, Mlinar B, Baccini G, Mayer U, Proft F, Hamon M, Schmitt AG, Corradetti R, Lanfumey L, Lesch KP. Gutknecht L, et al. PLoS One. 2012;7(8):e43157. doi: 10.1371/journal.pone.0043157. Epub 2012 Aug 17. PLoS One. 2012. PMID: 22912815 Free PMC article.

6

GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice.

Waider J, Proft F, Langlhofer G, Asan E, Lesch KP, Gutknecht L. Waider J, et al. Among authors: gutknecht l. Histochem Cell Biol. 2013 Feb;139(2):267-81. doi: 10.1007/s00418-012-1029-x. Epub 2012 Oct 11. Histochem Cell Biol. 2013. PMID: 23052836

7

Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.

Gutknecht L, Popp S, Waider J, Sommerlandt FM, Göppner C, Post A, Reif A, van den Hove D, Strekalova T, Schmitt A, Colaςo MB, Sommer C, Palme R, Lesch KP. Gutknecht L, et al. Psychopharmacology (Berl). 2015 Jul;232(14):2429-41. doi: 10.1007/s00213-015-3879-0. Epub 2015 Feb 27. Psychopharmacology (Berl). 2015. PMID: 25716307 Free PMC article.

8

Anxiety-related traits in mice with modified genes of the serotonergic pathway.

Lesch KP, Zeng Y, Reif A, Gutknecht L. Lesch KP, et al. Among authors: gutknecht l. Eur J Pharmacol. 2003 Nov 7;480(1-3):185-204. doi: 10.1016/j.ejphar.2003.08.106. Eur J Pharmacol. 2003. PMID: 14623362 Review.

9

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder.

Mössner R, Walitza S, Geller F, Scherag A, Gutknecht L, Jacob C, Bogusch L, Remschmidt H, Simons M, Herpertz-Dahlmann B, Fleischhaker C, Schulz E, Warnke A, Hinney A, Wewetzer C, Lesch KP. Mössner R, et al. Among authors: gutknecht l. Int J Neuropsychopharmacol. 2006 Aug;9(4):437-42. doi: 10.1017/S1461145705005997. Epub 2005 Sep 7. Int J Neuropsychopharmacol. 2006. PMID: 16146581 Free article.

10

The novel brain-specific tryptophan hydroxylase-2 gene in panic disorder.

Mössner R, Freitag CM, Gutknecht L, Reif A, Tauber R, Franke P, Fritze J, Wagner G, Peikert G, Wenda B, Sand P, Rietschel M, Garritsen H, Jacob C, Lesch KP, Deckert J. Mössner R, et al. Among authors: gutknecht l. J Psychopharmacol. 2006 Jul;20(4):547-52. doi: 10.1177/0269881106059704. Epub 2006 Jan 9. J Psychopharmacol. 2006. PMID: 16401665

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