Fujii N - Search Results

1

Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway.

Mahindroo N, Connelly MC, Punchihewa C, Yang L, Yan B, Fujii N. Mahindroo N, et al. Among authors: fujii n. Bioorg Med Chem. 2010 Jul 1;18(13):4801-11. doi: 10.1016/j.bmc.2010.05.001. Epub 2010 May 7. Bioorg Med Chem. 2010. PMID: 20605720 Free PMC article.

2

Design of a selective chemical probe for class I PDZ domains.

Fujii N, Shelat A, Hall RA, Guy RK. Fujii N, et al. Bioorg Med Chem Lett. 2007 Jan 15;17(2):546-8. doi: 10.1016/j.bmcl.2006.10.027. Epub 2006 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17074480

3

Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains.

Mayasundari A, Ferreira AM, He L, Mahindroo N, Bashford D, Fujii N. Mayasundari A, et al. Among authors: fujii n. Bioorg Med Chem Lett. 2008 Feb 1;18(3):942-5. doi: 10.1016/j.bmcl.2007.12.038. Epub 2007 Dec 23. Bioorg Med Chem Lett. 2008. PMID: 18180157

4

Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activity.

Mahindroo N, Punchihewa C, Bail AM, Fujii N. Mahindroo N, et al. Among authors: fujii n. Bioorg Med Chem Lett. 2008 Feb 1;18(3):946-9. doi: 10.1016/j.bmcl.2007.12.039. Epub 2007 Dec 23. Bioorg Med Chem Lett. 2008. PMID: 18180158

5

Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor-mediated transcription.

You L, Xu Z, Punchihewa C, Jablons DM, Fujii N. You L, et al. Among authors: fujii n. Mol Cancer Ther. 2008 Jun;7(6):1633-8. doi: 10.1158/1535-7163.MCT-08-0155. Mol Cancer Ther. 2008. PMID: 18566234

6

Hedgehog-Gli signaling pathway inhibitors as anticancer agents.

Mahindroo N, Punchihewa C, Fujii N. Mahindroo N, et al. Among authors: fujii n. J Med Chem. 2009 Jul 9;52(13):3829-45. doi: 10.1021/jm801420y. J Med Chem. 2009. PMID: 19309080 Free PMC article. Review. No abstract available.

7

Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.

Punchihewa C, Ferreira AM, Cassell R, Rodrigues P, Fujii N. Punchihewa C, et al. Among authors: fujii n. Protein Sci. 2009 May;18(5):994-1002. doi: 10.1002/pro.109. Protein Sci. 2009. PMID: 19388021 Free PMC article.

8

Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.

Mahindroo N, Connelly MC, Punchihewa C, Kimura H, Smeltzer MP, Wu S, Fujii N. Mahindroo N, et al. Among authors: fujii n. J Med Chem. 2009 Jul 23;52(14):4277-87. doi: 10.1021/jm900106f. J Med Chem. 2009. PMID: 19545120 Free PMC article.

9

A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription.

Actis M, Connelly MC, Mayasundari A, Punchihewa C, Fujii N. Actis M, et al. Among authors: fujii n. Biopolymers. 2011 Jan;95(1):24-30. doi: 10.1002/bip.21544. Biopolymers. 2011. PMID: 20872873

10

Functional regulation of cystic fibrosis transmembrane conductance regulator-containing macromolecular complexes: a small-molecule inhibitor approach.

Zhang W, Penmatsa H, Ren A, Punchihewa C, Lemoff A, Yan B, Fujii N, Naren AP. Zhang W, et al. Among authors: fujii n. Biochem J. 2011 Apr 15;435(2):451-62. doi: 10.1042/BJ20101725. Biochem J. 2011. PMID: 21299497 Free PMC article.

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