Brown J - Search Results

1

Priming innate immune responses to infection by cyclooxygenase inhibition kills antibiotic-susceptible and -resistant bacteria.

Stables MJ, Newson J, Ayoub SS, Brown J, Hyams CJ, Gilroy DW. Stables MJ, et al. Among authors: brown j. Blood. 2010 Oct 21;116(16):2950-9. doi: 10.1182/blood-2010-05-284844. Epub 2010 Jul 6. Blood. 2010. PMID: 20606163 Free PMC article.

2

The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice.

Brown JS, Hussell T, Gilliland SM, Holden DW, Paton JC, Ehrenstein MR, Walport MJ, Botto M. Brown JS, et al. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16969-74. doi: 10.1073/pnas.012669199. Epub 2002 Dec 11. Proc Natl Acad Sci U S A. 2002. PMID: 12477926 Free PMC article.

3

Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia.

Yuste J, Botto M, Paton JC, Holden DW, Brown JS. Yuste J, et al. Among authors: brown js. J Immunol. 2005 Aug 1;175(3):1813-9. doi: 10.4049/jimmunol.175.3.1813. J Immunol. 2005. PMID: 16034123

4

Roles of the alternative complement pathway and C1q during innate immunity to Streptococcus pyogenes.

Yuste J, Ali S, Sriskandan S, Hyams C, Botto M, Brown JS. Yuste J, et al. Among authors: brown js. J Immunol. 2006 May 15;176(10):6112-20. doi: 10.4049/jimmunol.176.10.6112. J Immunol. 2006. PMID: 16670320

5

Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae.

Yuste J, Botto M, Bottoms SE, Brown JS. Yuste J, et al. Among authors: brown js. PLoS Pathog. 2007 Sep 28;3(9):1208-19. doi: 10.1371/journal.ppat.0030120. PLoS Pathog. 2007. PMID: 17845072 Free PMC article.

6

Impaired opsonization with C3b and phagocytosis of Streptococcus pneumoniae in sera from subjects with defects in the classical complement pathway.

Yuste J, Sen A, Truedsson L, Jönsson G, Tay LS, Hyams C, Baxendale HE, Goldblatt F, Botto M, Brown JS. Yuste J, et al. Among authors: brown js. Infect Immun. 2008 Aug;76(8):3761-70. doi: 10.1128/IAI.00291-08. Epub 2008 Jun 9. Infect Immun. 2008. PMID: 18541650 Free PMC article.

7

The effects of PspC on complement-mediated immunity to Streptococcus pneumoniae vary with strain background and capsular serotype.

Yuste J, Khandavilli S, Ansari N, Muttardi K, Ismail L, Hyams C, Weiser J, Mitchell T, Brown JS. Yuste J, et al. Among authors: brown js. Infect Immun. 2010 Jan;78(1):283-92. doi: 10.1128/IAI.00541-09. Epub 2009 Nov 2. Infect Immun. 2010. PMID: 19884335 Free PMC article.

8

The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanisms.

Hyams C, Camberlein E, Cohen JM, Bax K, Brown JS. Hyams C, et al. Infect Immun. 2010 Feb;78(2):704-15. doi: 10.1128/IAI.00881-09. Epub 2009 Nov 30. Infect Immun. 2010. PMID: 19948837 Free PMC article.

9

Streptococcus pneumoniae resistance to complement-mediated immunity is dependent on the capsular serotype.

Hyams C, Yuste J, Bax K, Camberlein E, Weiser JN, Brown JS. Hyams C, et al. Among authors: brown js. Infect Immun. 2010 Feb;78(2):716-25. doi: 10.1128/IAI.01056-09. Epub 2009 Nov 30. Infect Immun. 2010. PMID: 19948838 Free PMC article.

10

C3b/iC3b deposition on Streptococcus pneumoniae is not affected by HIV infection.

Hyams C, Tam JC, Brown JS, Gordon SB. Hyams C, et al. PLoS One. 2010 Jan 26;5(1):e8902. doi: 10.1371/journal.pone.0008902. PLoS One. 2010. PMID: 20126656 Free PMC article.

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