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UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity.
Madsen L, Pedersen LM, Lillefosse HH, Fjaere E, Bronstad I, Hao Q, Petersen RK, Hallenborg P, Ma T, De Matteis R, Araujo P, Mercader J, Bonet ML, Hansen JB, Cannon B, Nedergaard J, Wang J, Cinti S, Voshol P, Døskeland SO, Kristiansen K. Madsen L, et al. Among authors: cinti s. PLoS One. 2010 Jun 30;5(6):e11391. doi: 10.1371/journal.pone.0011391. PLoS One. 2010. PMID: 20613988 Free PMC article.
Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.
Hansen JB, Jørgensen C, Petersen RK, Hallenborg P, De Matteis R, Bøye HA, Petrovic N, Enerbäck S, Nedergaard J, Cinti S, te Riele H, Kristiansen K. Hansen JB, et al. Among authors: cinti s. Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4112-7. doi: 10.1073/pnas.0301964101. Epub 2004 Mar 15. Proc Natl Acad Sci U S A. 2004. PMID: 15024128 Free PMC article.
p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.
Hallenborg P, Fjære E, Liaset B, Petersen RK, Murano I, Sonne SB, Falkerslev M, Winther S, Jensen BA, Ma T, Hansen JB, Cinti S, Blagoev B, Madsen L, Kristiansen K. Hallenborg P, et al. Among authors: cinti s. Am J Physiol Endocrinol Metab. 2016 Jan 15;310(2):E116-28. doi: 10.1152/ajpendo.00119.2015. Epub 2015 Nov 17. Am J Physiol Endocrinol Metab. 2016. PMID: 26578713 Free article.
Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice.
Banhos Danneskiold-Samsøe N, Sonne SB, Larsen JM, Hansen AN, Fjære E, Isidor MS, Petersen S, Henningsen J, Severi I, Sartini L, Schober Y, Wolf J, Nockher WA, Wolfrum C, Cinti S, Sina C, Hansen JB, Madsen L, Brix S, Kristiansen K. Banhos Danneskiold-Samsøe N, et al. Among authors: cinti s. Sci Rep. 2019 Jun 20;9(1):8979. doi: 10.1038/s41598-019-45062-w. Sci Rep. 2019. PMID: 31222118 Free PMC article.
The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.
Barbatelli G, Murano I, Madsen L, Hao Q, Jimenez M, Kristiansen K, Giacobino JP, De Matteis R, Cinti S. Barbatelli G, et al. Among authors: cinti s. Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1244-53. doi: 10.1152/ajpendo.00600.2009. Epub 2010 Mar 30. Am J Physiol Endocrinol Metab. 2010. PMID: 20354155 Free article.
ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes.
Hao Q, Hansen JB, Petersen RK, Hallenborg P, Jørgensen C, Cinti S, Larsen PJ, Steffensen KR, Wang H, Collins S, Wang J, Gustafsson JA, Madsen L, Kristiansen K. Hao Q, et al. Among authors: cinti s. Biochim Biophys Acta. 2010 Apr;1801(4):421-9. doi: 10.1016/j.bbalip.2009.11.008. Epub 2009 Dec 2. Biochim Biophys Acta. 2010. PMID: 19962449
Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice.
de Jong JMA, Sun W, Pires ND, Frontini A, Balaz M, Jespersen NZ, Feizi A, Petrovic K, Fischer AW, Bokhari MH, Niemi T, Nuutila P, Cinti S, Nielsen S, Scheele C, Virtanen K, Cannon B, Nedergaard J, Wolfrum C, Petrovic N. de Jong JMA, et al. Among authors: cinti s. Nat Metab. 2019 Aug;1(8):830-843. doi: 10.1038/s42255-019-0101-4. Epub 2019 Aug 19. Nat Metab. 2019. PMID: 32694768
452 results