Irwin I - Search Results

1

Tecarfarin, a novel vitamin K reductase antagonist, is not affected by CYP2C9 and CYP3A4 inhibition following concomitant administration of fluconazole in healthy participants.

Bavisotto LM, Ellis DJ, Milner PG, Combs DL, Irwin I, Canafax DM. Bavisotto LM, et al. Among authors: irwin i. J Clin Pharmacol. 2011 Apr;51(4):561-74. doi: 10.1177/0091270010370588. Epub 2010 Jul 9. J Clin Pharmacol. 2011. PMID: 20622200 Clinical Trial.

2

Effect of tecarfarin, a novel vitamin K epoxide reductase inhibitor, on coagulation in beagle dogs.

Choppin A, Irwin I, Lach L, McDonald MG, Rettie AE, Shao L, Becker C, Palme MP, Paliard X, Bowersox S, Dennis DM, Druzgala P. Choppin A, et al. Among authors: irwin i. Br J Pharmacol. 2009 Nov;158(6):1536-47. doi: 10.1111/j.1476-5381.2009.00420.x. Epub 2009 Oct 20. Br J Pharmacol. 2009. PMID: 19845677 Free PMC article.

3

The effect of diethyldithiocarbamate on the biodisposition of MPTP: an explanation for enhanced neurotoxicity.

Irwin I, Wu EY, DeLanney LE, Trevor A, Langston JW. Irwin I, et al. Eur J Pharmacol. 1987 Sep 11;141(2):209-17. doi: 10.1016/0014-2999(87)90265-2. Eur J Pharmacol. 1987. PMID: 2824216

4

Effects of benzoyltropine and tropacocaine on several cholinergic processes in the rat brain.

Meyer EM, Potter LT, De Vane CL, Irwin I, MacKay SL, Miller R, Ruttenber AJ. Meyer EM, et al. Among authors: irwin i. J Pharmacol Exp Ther. 1990 Aug;254(2):584-90. J Pharmacol Exp Ther. 1990. PMID: 1974643

5

Diethyldithiocarbamate and disulfiram inhibit MPP+ and dopamine uptake by striatal synaptosomes.

Di Monte D, Irwin I, Kupsch A, Cooper S, DeLanney LE, Langston JW. Di Monte D, et al. Among authors: irwin i. Eur J Pharmacol. 1989 Jul 4;166(1):23-9. doi: 10.1016/0014-2999(89)90679-1. Eur J Pharmacol. 1989. PMID: 2553428

6

Modulating role of dopamine on anesthetic requirements.

Segal IS, Walton JK, Irwin I, DeLanney LE, Ricaurte GA, Langston JW, Maze M. Segal IS, et al. Among authors: irwin i. Eur J Pharmacol. 1990 Sep 4;186(1):9-15. doi: 10.1016/0014-2999(90)94055-3. Eur J Pharmacol. 1990. PMID: 2282937 Free article.

7

Orally administered MDMA causes a long-term depletion of serotonin in rat brain.

Finnegan KT, Ricaurte GA, Ritchie LD, Irwin I, Peroutka SJ, Langston JW. Finnegan KT, et al. Among authors: irwin i. Brain Res. 1988 Apr 26;447(1):141-4. doi: 10.1016/0006-8993(88)90974-2. Brain Res. 1988. PMID: 2898273

8

Toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.

Di Monte DA, Wu EY, Delanney LE, Irwin I, Langston JW. Di Monte DA, et al. Among authors: irwin i. J Pharmacol Exp Ther. 1992 Apr;261(1):44-9. J Pharmacol Exp Ther. 1992. PMID: 1560384

9

Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.

Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW. Di Monte DA, et al. Among authors: irwin i. J Pharmacol Exp Ther. 1991 Aug;258(2):594-600. J Pharmacol Exp Ther. 1991. PMID: 1907660

10

The Neurotoxin l-Methyl-4-Phenyl-l,2,3,6-Tetrahydropyridine (MPTP): A Key to Parkinson's Disease?

Irwin I. Irwin I. Pharm Res. 1986 Feb;3(1):7-11. doi: 10.1023/A:1016312629652. Pharm Res. 1986. PMID: 24271351

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