Kaiser C - Search Results

1

Concise Two-Step Solution Phase Syntheses of four novel Dihydroquinazoline scaffolds.

Dietrich J, Kaiser C, Meurice N, Hulme C. Dietrich J, et al. Among authors: kaiser c. Tetrahedron Lett. 2010 Jul 28;51(30):3951-3955. doi: 10.1016/j.tetlet.2010.05.108. Tetrahedron Lett. 2010. PMID: 20625451 Free PMC article.

2

Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation.

Gunawan S, Ayaz M, De Moliner F, Frett B, Kaiser C, Patrick N, Xu Z, Hulme C. Gunawan S, et al. Among authors: kaiser c. Tetrahedron. 2012 Jul 8;68(27-28):5606-5611. doi: 10.1016/j.tet.2012.04.068. Epub 2012 Apr 26. Tetrahedron. 2012. PMID: 22923851 Free PMC article.

3

Softening the Rule of Five--where to draw the line?

Petit J, Meurice N, Kaiser C, Maggiora G. Petit J, et al. Among authors: kaiser c. Bioorg Med Chem. 2012 Sep 15;20(18):5343-51. doi: 10.1016/j.bmc.2011.11.064. Epub 2011 Dec 17. Bioorg Med Chem. 2012. PMID: 22222160 Free PMC article.

4

Chemogenomic analysis identifies Macbecin II as a compound specific for SMAD4-negative colon cancer cells.

Kaiser C, Meurice N, Gonzales IM, Arora S, Beaudry C, Bisanz KM, Robeson AC, Petit J, Azorsa DO. Kaiser C, et al. Chem Biol Drug Des. 2010 Apr;75(4):360-8. doi: 10.1111/j.1747-0285.2010.00949.x. Chem Biol Drug Des. 2010. PMID: 20331650

5

Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.

Wang Y, Kaiser CE, Frett B, Li HY. Wang Y, et al. J Med Chem. 2013 Jul 11;56(13):5219-30. doi: 10.1021/jm3017706. Epub 2013 Apr 23. J Med Chem. 2013. PMID: 23566315 Free PMC article. Review.

6

Gaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay.

Kaiser CE, Gokhale V, Yang D, Hurley LH. Kaiser CE, et al. Top Curr Chem. 2013;330:1-21. doi: 10.1007/128_2012_333. Top Curr Chem. 2013. PMID: 22752577 Free PMC article.

7

Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.

Kaiser CE, Van Ert NA, Agrawal P, Chawla R, Yang D, Hurley LH. Kaiser CE, et al. J Am Chem Soc. 2017 Jun 28;139(25):8522-8536. doi: 10.1021/jacs.7b02046. Epub 2017 Jun 15. J Am Chem Soc. 2017. PMID: 28570076 Free PMC article.

8

Oxazolones as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Sutin L, Andersson S, Bergquist L, Castro VM, Danielsson E, James S, Henriksson M, Johansson L, Kaiser C, Flyrén K, Williams M. Sutin L, et al. Among authors: kaiser c. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4837-40. doi: 10.1016/j.bmcl.2007.06.054. Epub 2007 Jun 20. Bioorg Med Chem Lett. 2007. PMID: 17600707

9

Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice.

Sundbom M, Kaiser C, Björkstrand E, Castro VM, Larsson C, Selén G, Nyhem CS, James SR. Sundbom M, et al. Among authors: kaiser c. BMC Pharmacol. 2008 Feb 12;8:3. doi: 10.1186/1471-2210-8-3. BMC Pharmacol. 2008. PMID: 18269730 Free PMC article.

10

Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation.

Kaiser C, James SR. Kaiser C, et al. BMC Biol. 2004 Nov 2;2:23. doi: 10.1186/1741-7007-2-23. BMC Biol. 2004. PMID: 15522123 Free PMC article.

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