Aboussekhra A - Search Results

1

Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule.

Ghebeh H, Lehe C, Barhoush E, Al-Romaih K, Tulbah A, Al-Alwan M, Hendrayani SF, Manogaran P, Alaiya A, Al-Tweigeri T, Aboussekhra A, Dermime S. Ghebeh H, et al. Among authors: aboussekhra a. Breast Cancer Res. 2010;12(4):R48. doi: 10.1186/bcr2605. Epub 2010 Jul 13. Breast Cancer Res. 2010. PMID: 20626886 Free PMC article.

2

The tumor suppressor p16(INK4a) gene is a regulator of apoptosis induced by ultraviolet light and cisplatin.

Al-Mohanna MA, Manogaran PS, Al-Mukhalafi Z, A Al-Hussein K, Aboussekhra A. Al-Mohanna MA, et al. Among authors: a al hussein k, aboussekhra a. Oncogene. 2004 Jan 8;23(1):201-12. doi: 10.1038/sj.onc.1206927. Oncogene. 2004. PMID: 14712225

3

Vincristine and lomustine induce apoptosis and p21(WAF1) up-regulation in medulloblastoma and normal human epithelial and fibroblast cells.

Shinwari Z, Manogaran PS, Alrokayan SA, Al-Hussein KA, Aboussekhra A. Shinwari Z, et al. Among authors: aboussekhra a. J Neurooncol. 2008 Apr;87(2):123-32. doi: 10.1007/s11060-007-9502-4. Epub 2007 Dec 6. J Neurooncol. 2008. PMID: 18058069

4

Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes.

Hawsawi NM, Ghebeh H, Hendrayani SF, Tulbah A, Al-Eid M, Al-Tweigeri T, Ajarim D, Alaiya A, Dermime S, Aboussekhra A. Hawsawi NM, et al. Among authors: aboussekhra a. Cancer Res. 2008 Apr 15;68(8):2717-25. doi: 10.1158/0008-5472.CAN-08-0192. Cancer Res. 2008. PMID: 18413739

5

Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells.

Elamin MH, Shinwari Z, Hendrayani SF, Al-Hindi H, Al-Shail E, Khafaga Y, Al-Kofide A, Aboussekhra A. Elamin MH, et al. Among authors: aboussekhra a. Mol Carcinog. 2010 Mar;49(3):302-14. doi: 10.1002/mc.20604. Mol Carcinog. 2010. PMID: 20025076

6

PAC, a novel curcumin analogue, has anti-breast cancer properties with higher efficiency on ER-negative cells.

Al-Hujaily EM, Mohamed AG, Al-Sharif I, Youssef KM, Manogaran PS, Al-Otaibi B, Al-Haza'a A, Al-Jammaz I, Al-Hussein K, Aboussekhra A. Al-Hujaily EM, et al. Among authors: aboussekhra a. Breast Cancer Res Treat. 2011 Jul;128(1):97-107. doi: 10.1007/s10549-010-1089-3. Epub 2010 Aug 1. Breast Cancer Res Treat. 2011. PMID: 20680677

7

The atr protein kinase controls UV-dependent upregulation of p16INK4A through inhibition of Skp2-related polyubiquitination/degradation.

Al-Khalaf HH, Hendrayani SF, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. Mol Cancer Res. 2011 Mar;9(3):311-9. doi: 10.1158/1541-7786.MCR-10-0506. Epub 2011 Jan 26. Mol Cancer Res. 2011. PMID: 21270107 Free article.

8

p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.

Al-Khalaf HH, Colak D, Al-Saif M, Al-Bakheet A, Hendrayani SF, Al-Yousef N, Kaya N, Khabar KS, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. PLoS One. 2011;6(7):e21111. doi: 10.1371/journal.pone.0021111. Epub 2011 Jul 20. PLoS One. 2011. PMID: 21799732 Free PMC article.

9

ATR controls the p21(WAF1/Cip1) protein up-regulation and apoptosis in response to low UV fluences.

Al-Khalaf HH, Hendrayani SF, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. Mol Carcinog. 2012 Dec;51(12):930-8. doi: 10.1002/mc.20864. Epub 2011 Oct 4. Mol Carcinog. 2012. PMID: 21976111

10

The p53 codon 72 polymorphism is associated with risk and early onset of breast cancer among Saudi women.

Al-Qasem A, Toulimat M, Tulbah A, Elkum N, Al-Tweigeri T, Aboussekhra A. Al-Qasem A, et al. Among authors: aboussekhra a. Oncol Lett. 2012 Apr 1;3(4):875-878. doi: 10.3892/ol.2012.581. Epub 2012 Jan 24. Oncol Lett. 2012. PMID: 22741010 Free PMC article.

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