Wong HN - Search Results

1

Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.

Haynes RK, Chan WC, Wong HN, Li KY, Wu WK, Fan KM, Sung HH, Williams ID, Prosperi D, Melato S, Coghi P, Monti D. Haynes RK, et al. Among authors: wong hn. ChemMedChem. 2010 Aug 2;5(8):1282-99. doi: 10.1002/cmdc.201000225. ChemMedChem. 2010. PMID: 20629071

2

Artemisone--a highly active antimalarial drug of the artemisinin class.

Haynes RK, Fugmann B, Stetter J, Rieckmann K, Heilmann HD, Chan HW, Cheung MK, Lam WL, Wong HN, Croft SL, Vivas L, Rattray L, Stewart L, Peters W, Robinson BL, Edstein MD, Kotecka B, Kyle DE, Beckermann B, Gerisch M, Radtke M, Schmuck G, Steinke W, Wollborn U, Schmeer K, Römer A. Haynes RK, et al. Among authors: wong hn. Angew Chem Int Ed Engl. 2006 Mar 20;45(13):2082-8. doi: 10.1002/anie.200503071. Angew Chem Int Ed Engl. 2006. PMID: 16444785 No abstract available.

3

Artesunate and dihydroartemisinin (DHA): unusual decomposition products formed under mild conditions and comments on the fitness of DHA as an antimalarial drug.

Haynes RK, Chan HW, Lung CM, Ng NC, Wong HN, Shek LY, Williams ID, Cartwright A, Gomes MF. Haynes RK, et al. Among authors: wong hn. ChemMedChem. 2007 Oct;2(10):1448-63. doi: 10.1002/cmdc.200700064. ChemMedChem. 2007. PMID: 17694524

4

Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities.

Haynes RK, Wong HN, Lee KW, Lung CM, Shek LY, Williams ID, Croft SL, Vivas L, Rattray L, Stewart L, Wong VK, Ko BC. Haynes RK, et al. Among authors: wong vk, wong hn. ChemMedChem. 2007 Oct;2(10):1464-79. doi: 10.1002/cmdc.200700065. ChemMedChem. 2007. PMID: 17768731

5

Artemisone uptake in Plasmodium falciparum-infected erythrocytes.

Pooley S, Fatih FA, Krishna S, Gerisch M, Haynes RK, Wong HN, Staines HM. Pooley S, et al. Among authors: wong hn. Antimicrob Agents Chemother. 2011 Feb;55(2):550-6. doi: 10.1128/AAC.01216-10. Epub 2010 Dec 6. Antimicrob Agents Chemother. 2011. PMID: 21135191 Free PMC article.

6

A partial convergence in action of methylene blue and artemisinins: antagonism with chloroquine, a reversal with verapamil, and an insight into the antimalarial activity of chloroquine.

Haynes RK, Cheu KW, Li KY, Tang MM, Wong HN, Chen MJ, Guo ZF, Guo ZH, Coghi P, Monti D. Haynes RK, et al. Among authors: wong hn. ChemMedChem. 2011 Sep 5;6(9):1603-15. doi: 10.1002/cmdc.201100184. Epub 2011 Jul 11. ChemMedChem. 2011. PMID: 21994127

7

Synthesis of artemiside and its effects in combination with conventional drugs against severe murine malaria.

Guo J, Guiguemde AW, Bentura-Marciano A, Clark J, Haynes RK, Chan WC, Wong HN, Hunt NH, Guy RK, Golenser J. Guo J, et al. Among authors: wong hn. Antimicrob Agents Chemother. 2012 Jan;56(1):163-73. doi: 10.1128/AAC.05006-11. Epub 2011 Oct 17. Antimicrob Agents Chemother. 2012. PMID: 22006004 Free PMC article.

8

Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model--a unifying proposal for drug action.

Haynes RK, Cheu KW, Chan HW, Wong HN, Li KY, Tang MM, Chen MJ, Guo ZF, Guo ZH, Sinniah K, Witte AB, Coghi P, Monti D. Haynes RK, et al. Among authors: wong hn. ChemMedChem. 2012 Dec;7(12):2204-26. doi: 10.1002/cmdc.201200383. Epub 2012 Oct 30. ChemMedChem. 2012. PMID: 23112085

9

The Case for Development of 11-Aza-artemisinins for Malaria.

Harmse R, Wong HN, Smit F, Haynes RK, N'Da DD. Harmse R, et al. Among authors: wong hn. Curr Med Chem. 2015;22(31):3607-30. doi: 10.2174/0929867322666150729115752. Curr Med Chem. 2015. PMID: 26219389 Review.

10

Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model.

Müller J, Aguado-Martínez A, Manser V, Wong HN, Haynes RK, Hemphill A. Müller J, et al. Among authors: wong hn. Vet Res. 2016 Feb 17;47:32. doi: 10.1186/s13567-016-0317-1. Vet Res. 2016. PMID: 26883424 Free PMC article.

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