Thway TM - Search Results

1

Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats.

Li X, Warmington KS, Niu QT, Asuncion FJ, Barrero M, Grisanti M, Dwyer D, Stouch B, Thway TM, Stolina M, Ominsky MS, Kostenuik PJ, Simonet WS, Paszty C, Ke HZ. Li X, et al. Among authors: thway tm. J Bone Miner Res. 2010 Dec;25(12):2647-56. doi: 10.1002/jbmr.182. Epub 2010 Jul 16. J Bone Miner Res. 2010. PMID: 20641040 Free article.

2

Measurement of Free Versus Total Therapeutic Monoclonal Antibody in Pharmacokinetic Assessment is Modulated by Affinity, Incubation Time, and Bioanalytical Platform.

Talbot JJ, Calamba D, Pai M, Ma M, Thway TM. Talbot JJ, et al. Among authors: thway tm. AAPS J. 2015 Nov;17(6):1446-54. doi: 10.1208/s12248-015-9807-8. Epub 2015 Aug 12. AAPS J. 2015. PMID: 26265093 Free PMC article.

3

Impact of anti-drug antibodies in preclinical pharmacokinetic assessment.

Thway TM, Magana I, Bautista A, Jawa V, Gu W, Ma M. Thway TM, et al. AAPS J. 2013 Jul;15(3):856-63. doi: 10.1208/s12248-013-9484-4. Epub 2013 May 8. AAPS J. 2013. PMID: 23653044 Free PMC article.

4

Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure.

Herskovitz J, Ryman J, Thway T, Lee S, Zhou L, Chirmule N, Meibohm B, Jawa V. Herskovitz J, et al. AAPS J. 2017 Mar;19(2):447-455. doi: 10.1208/s12248-016-0026-8. Epub 2017 Jan 9. AAPS J. 2017. PMID: 28070711

5

Utility of a Bayesian Mathematical Model to Predict the Impact of Immunogenicity on Pharmacokinetics of Therapeutic Proteins.

Kathman S Jr, Thway TM, Zhou L, Lee S, Yu S, Ma M, Chirmule N, Jawa V. Kathman S Jr, et al. Among authors: thway tm. AAPS J. 2016 Mar;18(2):424-31. doi: 10.1208/s12248-015-9853-2. Epub 2016 Jan 19. AAPS J. 2016. PMID: 26786568 Free PMC article.

6

Fundamentals of large-molecule protein therapeutic bioanalysis using ligand-binding assays.

Thway TM. Thway TM. Bioanalysis. 2016;8(1):11-7. doi: 10.4155/bio.15.199. Epub 2015 Dec 9. Bioanalysis. 2016. PMID: 26648176 Review.

7

Model-based strategy for bioanalytical method comparison: measurement of a soluble ligand as a biomarker.

Thway TM, Wang J, Brunner LA, Gu W, Magana I, Padbury G, Ma M. Thway TM, et al. J Pharm Biomed Anal. 2012 Jan 25;58:65-70. doi: 10.1016/j.jpba.2011.09.004. Epub 2011 Sep 10. J Pharm Biomed Anal. 2012. PMID: 22005590

8

Validation of a microfluidic platform to measure total therapeutic antibodies and incurred sample reanalysis performance.

Magana I, Macaraeg CR, Zhang L, Ma M, Thway TM. Magana I, et al. Among authors: thway tm. Bioanalysis. 2014;6(19):2623-33. doi: 10.4155/bio.14.129. Bioanalysis. 2014. PMID: 25411705

9

Bioanalytical method requirements and statistical considerations in incurred sample reanalysis for macromolecules.

Thway TM, Macaraeg CR, Calamba D, Brunner LA, Eschenberg M, Pourvasei R, Zhang L, Ma M, Desilva B. Thway TM, et al. Bioanalysis. 2010 Sep;2(9):1587-96. doi: 10.4155/bio.10.75. Bioanalysis. 2010. PMID: 21083287

10

Applications of a planar electrochemiluminescence platform to support regulated studies of macromolecules: benefits and limitations in assay range.

Thway T, Macaraeg C, Calamba D, Patel V, Tsoi J, Ma M, Lee J, Desilva B. Thway T, et al. J Pharm Biomed Anal. 2010 Feb 5;51(3):626-32. doi: 10.1016/j.jpba.2009.09.035. Epub 2009 Sep 30. J Pharm Biomed Anal. 2010. PMID: 19850429

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